september 27, 2023

Talabostat mesylate

Talabostat mesylate 

To Order Contact us: bjorn@lembcke.dk

Talabostat . mesylate
GW8231-10 10
EUR 110.2

Talabostat . mesylate
GW8231-50 50
EUR 298.9

Talabostat isomer mesylate
HY-13233B 10mg
EUR 666

Talabostat
HY-13233 50mg
EUR 734.4

AC710 (Mesylate)
HY-13493A 100mg
EUR 2620.8

AZ7550 Mesylate
HY-B0794B 10mg
EUR 666

AST2818 (mesylate)
HY-112870A 100mg
EUR 3847.2

A 80426 mesylate
B7025-10 10 mg
EUR 408
Description: A-80426 is a potent and selective ?2-adrenoceptor antagonist, it can block serotonin uptake and have putative antidepressant-like effects. It inhibits synaptosomal serotonin (5HT) uptake with an IC50 value of 13 nM and blocks [3H]-paroxetine binding to 5HT uptake sites with a Ki value of 3.8 nM.

A 80426 mesylate
B7025-50 50 mg
EUR 1531.2
Description: A-80426 is a potent and selective ?2-adrenoceptor antagonist, it can block serotonin uptake and have putative antidepressant-like effects. It inhibits synaptosomal serotonin (5HT) uptake with an IC50 value of 13 nM and blocks [3H]-paroxetine binding to 5HT uptake sites with a Ki value of 3.8 nM.

Gabexate mesylate
B3058-250 250 mg
EUR 351.6

Gabexate mesylate
B3058-50 50 mg
EUR 132

Eribulin mesylate
B3386-.5 500 ?g
EUR 1597.2
Description: Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules.

Eribulin mesylate
B3386-1 1 mg
EUR 1869.6
Description: Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules.

Apilimod mesylate
B1129-25 each
EUR 652.8

Apilimod mesylate
B1129-5 each
EUR 210

Apatinib mesylate
B1608-25 each
EUR 777.6

Apatinib mesylate
B1608-5 each
EUR 248.4

Camostat . mesylate
10-017 50 mg
EUR 410.64
Description: Camostat is an orally bioavailable trypsin-like protease inhibitor known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Camostat has been shown to inhibit the production of TNF-α and monocyte chemoattractant protein-1 by monocytes and to disrupt proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis. Protease regulation via camostat has also been reported to reversibly inhibit epithelial sodium channel function in human airway epithelial cell models. It is used in the treatment of some forms of cancer and is also effective against some viral infections (such as SARS, MERS or influenza), as well as inhibiting fibrosis in liver or kidney disease or pancreatitis. It suppresses pancreatitis-induced pain in rats following oral administration and is used to treat pancreatitis and reflux esophagitis after gastrectomy. It is an inhibitor of the enzyme transmembrane serine protease TMPRSS2 and partially blocks infection by SARS-CoV and human coronavirus NL63 in HeLa cells and entry of SARS-CoV2 (COVID-19) into lung cells in vitro.

Imatinib . mesylate
10-028 250 mg
EUR 471.12
Description: Imatinib mesylate is a multitarget tyrosine kinase inhibitor with antineoplastic activity. It is a potent and selective inhibitor of the kinases Bcr-Abl (IC50 = 38 nM), PDGFR and c-Kit, which are encoded by the bcr-abl oncogene as well as receptor tyrosine kinases encoded by c-Kit and platelet-derived growth factor receptor (PDGFR) oncogenes, which is useful in vitro and in vivo. Imatinib inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit and the proliferation of Bcr-Abl-dependent R10 cells and HMC-1 cells expressing constitutively active c-Kit in a concentration-dependent manner. Formulations containing imatinib have been used in the treatment of various cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis and myelodysplastic syndrome. Abelson (Abl) kinase inhibitors have been shown to inhibit replication of Ebola virus, coxsackievirus and vaccinia virus, but at different points of the virus life cycle. Imatinib inhibits replication of SARS-CoV and MERS-CoV in vitro by a novel mechanism of blocking coronavirus virion fusion with the endosomal membrane. Abl is also a potential drug target of SARS-CoV-2 and can possible inhibit the spread of COVID-19.

Gabexate mesylate
A4012-5 5 mg
EUR 129.6
Description: Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases with Ki values of 3.4nM and 180nM, respectively for human tryptase and bovine tryptase [1].

Gabexate mesylate
A4012-5.1 10 mM (in 1mL DMSO)
EUR 157.2
Description: Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases with Ki values of 3.4nM and 180nM, respectively for human tryptase and bovine tryptase [1].

Gabexate mesylate
A4012-50 50 mg
EUR 338.4
Description: Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases with Ki values of 3.4nM and 180nM, respectively for human tryptase and bovine tryptase [1].

Imatinib mesylate
20-abx076675
  • EUR 460.80
  • EUR 292.80
  • 100 mg
  • 20 mg

Imatinib Mesylate
E1KS1026 250mg
EUR 296.4

Imatinib (Mesylate)
HY-50946 5g
EUR 381.6

Gabexate (mesylate)
HY-B0385 10mM/1mL
EUR 214.8

Camostat mesylate
GP4306-100MG 100 mg
EUR 274.8

Camostat mesylate
GP4306-25MG 25 mg
EUR 122.4

Imatinib Mesylate
I031-100MG 100 mg
EUR 148.8

Imatinib Mesylate
I031-25MG 25 mg
EUR 75.6

Eribulin mesylate
HY-13442A 500ug
EUR 1465.2

Camostat (mesylate)
HY-13512 100mg
EUR 253.2

Exatecan (Mesylate)
HY-13631A 50mg
EUR 1712.4

Apilimod (mesylate)
HY-14644A 5mg
EUR 129.6

Camostat mesylate
GP4306-100 100
EUR 197.7

Camostat mesylate
GP4306-25 25
EUR 71.1

Imatinib mesylate
GP4375-100 100
EUR 110.2

Imatinib mesylate
GP4375-25 25
EUR 74.7

Pergolide mesylate
B1485-2.5 2.5 mg
EUR 201.6
Description: Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.

Pergolide mesylate
B1485-5.1 10 mM (in 1mL DMSO)
EUR 362.4
Description: Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.

Pergolide mesylate
B1485-S Evaluation Sample
EUR 97.2
Description: Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.

Naltriben mesylate
B5030-10 10 mg
EUR 369.6

Naltriben mesylate
B5030-50 50 mg
EUR 1363.2

Doxazosin Mesylate
A2884-100 100 mg
EUR 199.2
Description: Doxazosin Mesylate is a selective, long-lasting antagonist of ?1-adrenergic receptor [1].Doxazosin Mesylate has been reported to potentiate contraction response to 5-HT in a dose-dependent manner [1].

Doxazosin Mesylate
A2884-5.1 10 mM (in 1mL DMSO)
EUR 170.4
Description: Doxazosin Mesylate is a selective, long-lasting antagonist of ?1-adrenergic receptor [1].Doxazosin Mesylate has been reported to potentiate contraction response to 5-HT in a dose-dependent manner [1].

Doxazosin Mesylate
A2884-50 50 mg
EUR 157.2
Description: Doxazosin Mesylate is a selective, long-lasting antagonist of ?1-adrenergic receptor [1].Doxazosin Mesylate has been reported to potentiate contraction response to 5-HT in a dose-dependent manner [1].

Masitinib (mesylate)
HY-10209A 10mg
EUR 142.8

Almitrine mesylate
HY-107319 50mg
EUR 224.4

Obatoclax (Mesylate)
HY-10969 100mg
EUR 655.2

Erlotinib (mesylate)
HY-12008A 500mg
EUR 183.6

Doxazosin (mesylate)
HY-B0098A 10mM/1mL
EUR 165.6

Doxazosin mesylate
GP9708-100MG 100 mg
EUR 74.4

Doxazosin mesylate
GP9708-250MG 250 mg
EUR 111.6

Pergolide (mesylate)
HY-13720A 25mg
EUR 258

Doxazosin mesylate
GP9708-100 100
EUR 31.7

Doxazosin mesylate
GP9708-250 250
EUR 62.5

Saquinavir mesylate
B1999-10 each
EUR 170.4

Pefloxacin Mesylate
B2003-100 100 mg
EUR 115.2
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse)

Pefloxacin Mesylate
B2003-10000 10 g
EUR 129.6
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse)

Pefloxacin Mesylate
B2003-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse)

Pefloxacin Mesylate
B2003-50000 50 g
EUR 268.8
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse)

Reboxetine mesylate
B2124-10 10 mg
EUR 166.8
Description: Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.

Reboxetine mesylate
B2124-50 50 mg
EUR 517.2
Description: Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.

Reboxetine mesylate
B2124-S Evaluation Sample
EUR 97.2
Description: Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.

Pritelivir mesylate
B2154-25 each
EUR 548.4

Pritelivir mesylate
B2154-5 each
EUR 183.6

Ibutamoren mesylate
B2400-25 each
EUR 418.8

Ibutamoren mesylate
B2400-5 each
EUR 157.2

Nafamostat . mesylate
10-031 50 mg
EUR 440.88
Description: Nafamostat mesylate is a cell permeable broad spectrum potent and reversible synthetic serine protease inhibitor and kallikrein inhibitor in vitro and in vivo. It inhibits trypsin (Ki=15nM), tryptase (Ki=95.3pM) and additional proteases in the coagulation cascade including thrombin (Ki=0.84µM). Nafamostat mesylate is a short-acting anticoagulant with anti-inflammatory, anticancer and antiviral properties. As a potential anticancer agent, it blocks canonical NF-κB signaling, targets TNFR1-stimulated cleavage of caspase families and the tryptase of mast cells to improve therapeutic outcome and to ameliorate cancer therapy resistance and avoid immune resistance. It has been shown to reduce eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Inhibits the demethylase activity of the fat mass and obesity-associated protein (FTO). As antiviral agent, it inhibits Ebola virus, MERS-CoV and SARS-CoV-2 infection in vitro and potentially the spread of COVID-19. Nafamostat mesylate inhibits TMPRSS2-dependent host cell entry of MERS-CoV. It is also an inhibitor of the enzyme transmembrane serine protease TMPRSS2 and blocks the entry of SARS-CoV-2 (COVID-19) into lung cells in vitro, with roughly 15-fold higher efficiency than Camostat mesylate (Prod. No. AG-CR1-3716), with an EC50 in the low nanomolar range.

Nelfinavir . mesylate
10-032 50 mg
EUR 486.24
Description: Nelfinavir is an orally bioavailable competitive inhibitor of the human immunodeficiency virus. It potently inhibits HIV-1 (Ki=2nM) and HIV-2 protease in vitro. HIV-1 protease is important for the replication of the virus within the cell and the release of mature viral particles from the infected cell. Formulations containing nelfinavir have been used in combination with HIV reverse transcriptase inhibitors for the treatment of AIDS. Nelfinavir shows other antimicrobial and antiviral activity. It inhibits maturation and export of the Herpes Simplex 1 virus and the Kaposi's Sarcoma virus, replication of SARS-CoV and also replication of SARS-CoV-2, cause for the epidemic COVID-19. Has potent anti-cancer activity against a broad selection fo cancer cell types. Shown to induce apoptosis, autophagy, cell cycle arrest and endoplasmic reticulum stress, which consequently leads to cancer cell death. Shown to inhibit the Akt/PKB signaling pathway. It acts as an antifibrotic agent and is used to treat pulmonary fibrosis in patients with systemic sclerosis (SSc) and reduces inflammation by activating protein phosphatase 2 (PP-2) and blocking mitogen-activated protein kinases (MAPK) signaling in macrophages.

Saquinavir . mesylate
10-044 50 mg
EUR 440.88
Description: Saquinavir is an antiretroviral inhibitor of the human immunodeficiency virus. It potently inhibits HIV-1 (Ki=0.12nM) and HIV-2 (Ki<0.1nM) protease in vitro. HIV-1 protease is important for the replication of the virus within the cell and the release of mature viral particles from the infected cell. Formulations containing saquinavir have been used in combination with other inhibitors for the treatment of AIDS. Saquinavir shows other antimicrobial and antiviral activity. Potential SARS-CoV-2 replication inhibitor, responsible for COVID-19. Shows anti-cancer activity. Shown to induce apoptosis, autophagy and endoplasmic reticulum stress, which consequently leads to cancer cell death. Anti-inflammatory agent. Blocks cathepsin V and thereby inhibits disulfide HMGB1-induced TLR4 activation and cytokine production.

Rasagiline mesylate
2237-250 each
EUR 301.2

Rasagiline mesylate
2237-50 each
EUR 130.8

Nafamostat Mesylate
1760-10 each
EUR 164.4

Nafamostat Mesylate
1760-50 each
EUR 424.8

Ibutamoren Mesylate
A3481-10 10 mg
EUR 274.8
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor.

Ibutamoren Mesylate
A3481-25 25 mg
EUR 571.2
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor.

Ibutamoren Mesylate
A3481-5 5 mg
EUR 172.8
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor.

Ibutamoren Mesylate
A3481-50 50 mg
EUR 967.2
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor.

Nelfinavir Mesylate
A3653-10 10 mg
EUR 151.2
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell.

Nelfinavir Mesylate
A3653-5 5 mg
EUR 129.6
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell.

Nelfinavir Mesylate
A3653-5.1 10 mM (in 1mL DMSO)
EUR 164.4
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell.

Nelfinavir Mesylate
A3653-50 50 mg
EUR 393.6
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell.

Saquinavir mesylate
A3791-10 10 mg
EUR 129.6
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2].

Saquinavir mesylate
A3791-200 200 mg
EUR 847.2
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2].

Saquinavir mesylate
A3791-25 25 mg
EUR 160.8
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2].

Saquinavir mesylate
A3791-5.1 10 mM (in 1mL DMSO)
EUR 146.4
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2].

Rasagiline Mesylate
A4366-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Rasagiline mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.

Rasagiline Mesylate
A4366-50 50 mg
EUR 153.6
Description: Rasagiline mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.

Safinamide Mesylate
A4368-10 10 mg
EUR 216
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM.

Safinamide Mesylate
A4368-5.1 10 mM (in 1mL DMSO)
EUR 321.6
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM.

Safinamide Mesylate
A4368-50 50 mg
EUR 559.2
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM.

Safinamide Mesylate
A4368-500 500 mg
EUR 1131.6
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM.

Sildenafil mesylate
B6073-25 25 mg
EUR 129.6
Description: IC50: 3.5 nMSildenafil mesylate is an inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).PDE5 is the predominant phosphodiesterase in the corpus cavernosum.

Sildenafil mesylate
B6073-50 50 mg
EUR 170.4
Description: IC50: 3.5 nMSildenafil mesylate is an inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).PDE5 is the predominant phosphodiesterase in the corpus cavernosum.

Sildenafil mesylate
B6073-500 500 mg
EUR 714
Description: IC50: 3.5 nMSildenafil mesylate is an inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).PDE5 is the predominant phosphodiesterase in the corpus cavernosum.

Tetrindole mesylate
B6419-10 10 mg
EUR 321.6

Tetrindole mesylate
B6419-50 50 mg
EUR 1167.6

Talabostat mesylate