Talabostat mesylate
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Talabostat . mesylate |
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GW8231-10 | Glentham Life Sciences | 10 | EUR 110.2 |
Talabostat . mesylate |
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GW8231-50 | Glentham Life Sciences | 50 | EUR 298.9 |
Talabostat isomer mesylate |
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HY-13233B | MedChemExpress | 10mg | EUR 666 |
Talabostat |
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HY-13233 | MedChemExpress | 50mg | EUR 734.4 |
AC710 (Mesylate) |
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HY-13493A | MedChemExpress | 100mg | EUR 2620.8 |
AZ7550 Mesylate |
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HY-B0794B | MedChemExpress | 10mg | EUR 666 |
AST2818 (mesylate) |
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HY-112870A | MedChemExpress | 100mg | EUR 3847.2 |
A 80426 mesylate |
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B7025-10 | ApexBio | 10 mg | EUR 408 |
Description: A-80426 is a potent and selective ?2-adrenoceptor antagonist, it can block serotonin uptake and have putative antidepressant-like effects. It inhibits synaptosomal serotonin (5HT) uptake with an IC50 value of 13 nM and blocks [3H]-paroxetine binding to 5HT uptake sites with a Ki value of 3.8 nM. |
A 80426 mesylate |
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B7025-50 | ApexBio | 50 mg | EUR 1531.2 |
Description: A-80426 is a potent and selective ?2-adrenoceptor antagonist, it can block serotonin uptake and have putative antidepressant-like effects. It inhibits synaptosomal serotonin (5HT) uptake with an IC50 value of 13 nM and blocks [3H]-paroxetine binding to 5HT uptake sites with a Ki value of 3.8 nM. |
Gabexate mesylate |
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B3058-250 | Biovision | 250 mg | EUR 351.6 |
Gabexate mesylate |
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B3058-50 | Biovision | 50 mg | EUR 132 |
Eribulin mesylate |
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B3386-.5 | ApexBio | 500 ?g | EUR 1597.2 |
Description: Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules. |
Eribulin mesylate |
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B3386-1 | ApexBio | 1 mg | EUR 1869.6 |
Description: Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules. |
Apilimod mesylate |
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B1129-25 | Biovision | each | EUR 652.8 |
Apilimod mesylate |
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B1129-5 | Biovision | each | EUR 210 |
Apatinib mesylate |
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B1608-25 | Biovision | each | EUR 777.6 |
Apatinib mesylate |
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B1608-5 | Biovision | each | EUR 248.4 |
Camostat . mesylate |
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10-017 | ProSci | 50 mg | EUR 410.64 |
Description: Camostat is an orally bioavailable trypsin-like protease inhibitor known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Camostat has been shown to inhibit the production of TNF-α and monocyte chemoattractant protein-1 by monocytes and to disrupt proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis. Protease regulation via camostat has also been reported to reversibly inhibit epithelial sodium channel function in human airway epithelial cell models. It is used in the treatment of some forms of cancer and is also effective against some viral infections (such as SARS, MERS or influenza), as well as inhibiting fibrosis in liver or kidney disease or pancreatitis. It suppresses pancreatitis-induced pain in rats following oral administration and is used to treat pancreatitis and reflux esophagitis after gastrectomy. It is an inhibitor of the enzyme transmembrane serine protease TMPRSS2 and partially blocks infection by SARS-CoV and human coronavirus NL63 in HeLa cells and entry of SARS-CoV2 (COVID-19) into lung cells in vitro. |
Imatinib . mesylate |
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10-028 | ProSci | 250 mg | EUR 471.12 |
Description: Imatinib mesylate is a multitarget tyrosine kinase inhibitor with antineoplastic activity. It is a potent and selective inhibitor of the kinases Bcr-Abl (IC50 = 38 nM), PDGFR and c-Kit, which are encoded by the bcr-abl oncogene as well as receptor tyrosine kinases encoded by c-Kit and platelet-derived growth factor receptor (PDGFR) oncogenes, which is useful in vitro and in vivo. Imatinib inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit and the proliferation of Bcr-Abl-dependent R10 cells and HMC-1 cells expressing constitutively active c-Kit in a concentration-dependent manner. Formulations containing imatinib have been used in the treatment of various cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis and myelodysplastic syndrome. Abelson (Abl) kinase inhibitors have been shown to inhibit replication of Ebola virus, coxsackievirus and vaccinia virus, but at different points of the virus life cycle. Imatinib inhibits replication of SARS-CoV and MERS-CoV in vitro by a novel mechanism of blocking coronavirus virion fusion with the endosomal membrane. Abl is also a potential drug target of SARS-CoV-2 and can possible inhibit the spread of COVID-19. |
Gabexate mesylate |
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A4012-5 | ApexBio | 5 mg | EUR 129.6 |
Description: Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases with Ki values of 3.4nM and 180nM, respectively for human tryptase and bovine tryptase [1]. |
Gabexate mesylate |
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A4012-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 157.2 |
Description: Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases with Ki values of 3.4nM and 180nM, respectively for human tryptase and bovine tryptase [1]. |
Gabexate mesylate |
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A4012-50 | ApexBio | 50 mg | EUR 338.4 |
Description: Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases with Ki values of 3.4nM and 180nM, respectively for human tryptase and bovine tryptase [1]. |
Imatinib mesylate |
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20-abx076675 | Abbexa |
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Imatinib Mesylate |
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E1KS1026 | EnoGene | 250mg | EUR 296.4 |
Imatinib (Mesylate) |
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HY-50946 | MedChemExpress | 5g | EUR 381.6 |
Gabexate (mesylate) |
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HY-B0385 | MedChemExpress | 10mM/1mL | EUR 214.8 |
Camostat mesylate |
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GP4306-100MG | Glentham Life Sciences | 100 mg | EUR 274.8 |
Camostat mesylate |
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GP4306-25MG | Glentham Life Sciences | 25 mg | EUR 122.4 |
Imatinib Mesylate |
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I031-100MG | TOKU-E | 100 mg | EUR 148.8 |
Imatinib Mesylate |
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I031-25MG | TOKU-E | 25 mg | EUR 75.6 |
Eribulin mesylate |
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HY-13442A | MedChemExpress | 500ug | EUR 1465.2 |
Camostat (mesylate) |
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HY-13512 | MedChemExpress | 100mg | EUR 253.2 |
Exatecan (Mesylate) |
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HY-13631A | MedChemExpress | 50mg | EUR 1712.4 |
Apilimod (mesylate) |
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HY-14644A | MedChemExpress | 5mg | EUR 129.6 |
Camostat mesylate |
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GP4306-100 | Glentham Life Sciences | 100 | EUR 197.7 |
Camostat mesylate |
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GP4306-25 | Glentham Life Sciences | 25 | EUR 71.1 |
Imatinib mesylate |
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GP4375-100 | Glentham Life Sciences | 100 | EUR 110.2 |
Imatinib mesylate |
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GP4375-25 | Glentham Life Sciences | 25 | EUR 74.7 |
Pergolide mesylate |
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B1485-2.5 | ApexBio | 2.5 mg | EUR 201.6 |
Description: Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist. |
Pergolide mesylate |
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B1485-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 362.4 |
Description: Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist. |
Pergolide mesylate |
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B1485-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist. |
Naltriben mesylate |
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B5030-10 | ApexBio | 10 mg | EUR 369.6 |
Naltriben mesylate |
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B5030-50 | ApexBio | 50 mg | EUR 1363.2 |
Doxazosin Mesylate |
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A2884-100 | ApexBio | 100 mg | EUR 199.2 |
Description: Doxazosin Mesylate is a selective, long-lasting antagonist of ?1-adrenergic receptor [1].Doxazosin Mesylate has been reported to potentiate contraction response to 5-HT in a dose-dependent manner [1]. |
Doxazosin Mesylate |
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A2884-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 170.4 |
Description: Doxazosin Mesylate is a selective, long-lasting antagonist of ?1-adrenergic receptor [1].Doxazosin Mesylate has been reported to potentiate contraction response to 5-HT in a dose-dependent manner [1]. |
Doxazosin Mesylate |
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A2884-50 | ApexBio | 50 mg | EUR 157.2 |
Description: Doxazosin Mesylate is a selective, long-lasting antagonist of ?1-adrenergic receptor [1].Doxazosin Mesylate has been reported to potentiate contraction response to 5-HT in a dose-dependent manner [1]. |
Masitinib (mesylate) |
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HY-10209A | MedChemExpress | 10mg | EUR 142.8 |
Almitrine mesylate |
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HY-107319 | MedChemExpress | 50mg | EUR 224.4 |
Obatoclax (Mesylate) |
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HY-10969 | MedChemExpress | 100mg | EUR 655.2 |
Erlotinib (mesylate) |
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HY-12008A | MedChemExpress | 500mg | EUR 183.6 |
Doxazosin (mesylate) |
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HY-B0098A | MedChemExpress | 10mM/1mL | EUR 165.6 |
Doxazosin mesylate |
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GP9708-100MG | Glentham Life Sciences | 100 mg | EUR 74.4 |
Doxazosin mesylate |
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GP9708-250MG | Glentham Life Sciences | 250 mg | EUR 111.6 |
Pergolide (mesylate) |
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HY-13720A | MedChemExpress | 25mg | EUR 258 |
Doxazosin mesylate |
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GP9708-100 | Glentham Life Sciences | 100 | EUR 31.7 |
Doxazosin mesylate |
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GP9708-250 | Glentham Life Sciences | 250 | EUR 62.5 |
Saquinavir mesylate |
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B1999-10 | Biovision | each | EUR 170.4 |
Pefloxacin Mesylate |
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B2003-100 | ApexBio | 100 mg | EUR 115.2 |
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) |
Pefloxacin Mesylate |
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B2003-10000 | ApexBio | 10 g | EUR 129.6 |
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) |
Pefloxacin Mesylate |
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B2003-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 129.6 |
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) |
Pefloxacin Mesylate |
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B2003-50000 | ApexBio | 50 g | EUR 268.8 |
Description: Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) |
Reboxetine mesylate |
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B2124-10 | ApexBio | 10 mg | EUR 166.8 |
Description: Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM. |
Reboxetine mesylate |
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B2124-50 | ApexBio | 50 mg | EUR 517.2 |
Description: Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM. |
Reboxetine mesylate |
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B2124-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM. |
Pritelivir mesylate |
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B2154-25 | Biovision | each | EUR 548.4 |
Pritelivir mesylate |
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B2154-5 | Biovision | each | EUR 183.6 |
Ibutamoren mesylate |
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B2400-25 | Biovision | each | EUR 418.8 |
Ibutamoren mesylate |
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B2400-5 | Biovision | each | EUR 157.2 |
Nafamostat . mesylate |
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10-031 | ProSci | 50 mg | EUR 440.88 |
Description: Nafamostat mesylate is a cell permeable broad spectrum potent and reversible synthetic serine protease inhibitor and kallikrein inhibitor in vitro and in vivo. It inhibits trypsin (Ki=15nM), tryptase (Ki=95.3pM) and additional proteases in the coagulation cascade including thrombin (Ki=0.84µM). Nafamostat mesylate is a short-acting anticoagulant with anti-inflammatory, anticancer and antiviral properties. As a potential anticancer agent, it blocks canonical NF-κB signaling, targets TNFR1-stimulated cleavage of caspase families and the tryptase of mast cells to improve therapeutic outcome and to ameliorate cancer therapy resistance and avoid immune resistance. It has been shown to reduce eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Inhibits the demethylase activity of the fat mass and obesity-associated protein (FTO). As antiviral agent, it inhibits Ebola virus, MERS-CoV and SARS-CoV-2 infection in vitro and potentially the spread of COVID-19. Nafamostat mesylate inhibits TMPRSS2-dependent host cell entry of MERS-CoV. It is also an inhibitor of the enzyme transmembrane serine protease TMPRSS2 and blocks the entry of SARS-CoV-2 (COVID-19) into lung cells in vitro, with roughly 15-fold higher efficiency than Camostat mesylate (Prod. No. AG-CR1-3716), with an EC50 in the low nanomolar range. |
Nelfinavir . mesylate |
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10-032 | ProSci | 50 mg | EUR 486.24 |
Description: Nelfinavir is an orally bioavailable competitive inhibitor of the human immunodeficiency virus. It potently inhibits HIV-1 (Ki=2nM) and HIV-2 protease in vitro. HIV-1 protease is important for the replication of the virus within the cell and the release of mature viral particles from the infected cell. Formulations containing nelfinavir have been used in combination with HIV reverse transcriptase inhibitors for the treatment of AIDS. Nelfinavir shows other antimicrobial and antiviral activity. It inhibits maturation and export of the Herpes Simplex 1 virus and the Kaposi's Sarcoma virus, replication of SARS-CoV and also replication of SARS-CoV-2, cause for the epidemic COVID-19. Has potent anti-cancer activity against a broad selection fo cancer cell types. Shown to induce apoptosis, autophagy, cell cycle arrest and endoplasmic reticulum stress, which consequently leads to cancer cell death. Shown to inhibit the Akt/PKB signaling pathway. It acts as an antifibrotic agent and is used to treat pulmonary fibrosis in patients with systemic sclerosis (SSc) and reduces inflammation by activating protein phosphatase 2 (PP-2) and blocking mitogen-activated protein kinases (MAPK) signaling in macrophages. |
Saquinavir . mesylate |
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10-044 | ProSci | 50 mg | EUR 440.88 |
Description: Saquinavir is an antiretroviral inhibitor of the human immunodeficiency virus. It potently inhibits HIV-1 (Ki=0.12nM) and HIV-2 (Ki<0.1nM) protease in vitro. HIV-1 protease is important for the replication of the virus within the cell and the release of mature viral particles from the infected cell. Formulations containing saquinavir have been used in combination with other inhibitors for the treatment of AIDS. Saquinavir shows other antimicrobial and antiviral activity. Potential SARS-CoV-2 replication inhibitor, responsible for COVID-19. Shows anti-cancer activity. Shown to induce apoptosis, autophagy and endoplasmic reticulum stress, which consequently leads to cancer cell death. Anti-inflammatory agent. Blocks cathepsin V and thereby inhibits disulfide HMGB1-induced TLR4 activation and cytokine production. |
Rasagiline mesylate |
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2237-250 | Biovision | each | EUR 301.2 |
Rasagiline mesylate |
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2237-50 | Biovision | each | EUR 130.8 |
Nafamostat Mesylate |
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1760-10 | Biovision | each | EUR 164.4 |
Nafamostat Mesylate |
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1760-50 | Biovision | each | EUR 424.8 |
Ibutamoren Mesylate |
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A3481-10 | ApexBio | 10 mg | EUR 274.8 |
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor. |
Ibutamoren Mesylate |
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A3481-25 | ApexBio | 25 mg | EUR 571.2 |
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor. |
Ibutamoren Mesylate |
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A3481-5 | ApexBio | 5 mg | EUR 172.8 |
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor. |
Ibutamoren Mesylate |
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A3481-50 | ApexBio | 50 mg | EUR 967.2 |
Description: Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor. |
Nelfinavir Mesylate |
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A3653-10 | ApexBio | 10 mg | EUR 151.2 |
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell. |
Nelfinavir Mesylate |
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A3653-5 | ApexBio | 5 mg | EUR 129.6 |
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell. |
Nelfinavir Mesylate |
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A3653-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 164.4 |
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell. |
Nelfinavir Mesylate |
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A3653-50 | ApexBio | 50 mg | EUR 393.6 |
Description: Nelfinavir Mesylate is a potent inhibitor of HIV-1 protease [1].HIV-1 protease is a constitutive enzyme that processes gag and gag-pol polyproteins for packaging into the nascent virion actively budding from a productively infected cell. |
Saquinavir mesylate |
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A3791-10 | ApexBio | 10 mg | EUR 129.6 |
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2]. |
Saquinavir mesylate |
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A3791-200 | ApexBio | 200 mg | EUR 847.2 |
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2]. |
Saquinavir mesylate |
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A3791-25 | ApexBio | 25 mg | EUR 160.8 |
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2]. |
Saquinavir mesylate |
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A3791-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 146.4 |
Description: Saquinavir is a potent inhibitor HIV protease with Ki value of 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease[1].HIV protease is essential for release of mature viral and viral replication which is a retroviral aspartyl protease[2]. |
Rasagiline Mesylate |
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A4366-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Rasagiline mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease. |
Rasagiline Mesylate |
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A4366-50 | ApexBio | 50 mg | EUR 153.6 |
Description: Rasagiline mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease. |
Safinamide Mesylate |
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A4368-10 | ApexBio | 10 mg | EUR 216 |
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM. |
Safinamide Mesylate |
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A4368-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 321.6 |
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM. |
Safinamide Mesylate |
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A4368-50 | ApexBio | 50 mg | EUR 559.2 |
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM. |
Safinamide Mesylate |
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A4368-500 | ApexBio | 500 mg | EUR 1131.6 |
Description: Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM. |
Sildenafil mesylate |
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B6073-25 | ApexBio | 25 mg | EUR 129.6 |
Description: IC50: 3.5 nMSildenafil mesylate is an inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).PDE5 is the predominant phosphodiesterase in the corpus cavernosum. |
Sildenafil mesylate |
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B6073-50 | ApexBio | 50 mg | EUR 170.4 |
Description: IC50: 3.5 nMSildenafil mesylate is an inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).PDE5 is the predominant phosphodiesterase in the corpus cavernosum. |
Sildenafil mesylate |
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B6073-500 | ApexBio | 500 mg | EUR 714 |
Description: IC50: 3.5 nMSildenafil mesylate is an inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).PDE5 is the predominant phosphodiesterase in the corpus cavernosum. |
Tetrindole mesylate |
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B6419-10 | ApexBio | 10 mg | EUR 321.6 |
Tetrindole mesylate |
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B6419-50 | ApexBio | 50 mg | EUR 1167.6 |