Disentangling primer interactions improves SARS-CoV-2 genome sequencing by multiplex tiling PCR
Since December 2019, the coronavirus illness 2019 (COVID-19) brought on by a novel coronavirus SARS-CoV-2 has quickly unfold to nearly each nation on this planet. Quickly after the pandemic was acknowledged by epidemiologists, a bunch of biologists comprising the ARTIC Community, has devised a multiplexed polymerase chain response (PCR) protocol and primer set for focused whole-genome amplification of SARS-CoV-2.
The ARTIC primer set amplifies 98 amplicons, that are separated solely in two PCRs, throughout a virtually complete viral genome. The unique primer set and protocol confirmed a reasonably small amplification bias when scientific samples with comparatively excessive viral hundreds had been used.
Nonetheless, as pattern’s viral load turn into low, speedy lower in abundances of a number of amplicons had been seen. On this report, we’ll present that dimer formations between some primers are the key explanation for protection bias within the multiplex PCR. Based mostly on this, we suggest 12 different primers in whole within the ARTIC primer set that had been predicted to be concerned in 14 primer interactions.
The ensuing primer set, model N1 (NIID-1), displays improved general protection in comparison with the ARTIC Community’s unique (V1) and modified (V3) primer set.
RLIM Polyclonal Antibody |
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29447-50ul | SAB | 50ul | EUR 224.4 |
RLIM siRNA |
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20-abx931585 | Abbexa |
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RLIM siRNA |
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20-abx931586 | Abbexa |
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RLIM Polyclonal Conjugated Antibody |
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C29447 | SAB | 100ul | EUR 476.4 |
RLIM Blocking Peptide |
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DF12723-BP | Affbiotech | 1mg | EUR 234 |
RLIM Rabbit pAb |
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A15837-100ul | Abclonal | 100 ul | EUR 369.6 |
RLIM Rabbit pAb |
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A15837-200ul | Abclonal | 200 ul | EUR 550.8 |
RLIM Rabbit pAb |
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A15837-20ul | Abclonal | 20 ul | EUR 219.6 |
RLIM Rabbit pAb |
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A15837-50ul | Abclonal | 50 ul | EUR 267.6 |
Human E3 ubiquitin- protein ligase RLIM, RLIM ELISA KIT |
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ELI-40904h | Lifescience Market | 96 Tests | EUR 988.8 |
Mouse E3 ubiquitin- protein ligase RLIM, Rlim ELISA KIT |
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ELI-52811m | Lifescience Market | 96 Tests | EUR 1038 |
Mouse RLIM shRNA Plasmid |
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20-abx972467 | Abbexa |
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Human RLIM shRNA Plasmid |
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20-abx959551 | Abbexa |
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RLIM ELISA KIT|Human |
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EF002487 | Lifescience Market | 96 Tests | EUR 826.8 |
RLIM Recombinant Protein (Human) |
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RP026497 | ABM | 100 ug | Ask for price |
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RP226193 | ABM | 100 ug | Ask for price |
RLIM Recombinant Protein (Mouse) |
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RP168323 | ABM | 100 ug | Ask for price |
Polyclonal Goat anti-GST α-form |
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GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST μ-form |
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GST-ANTI-2 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST p-form |
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Rlim ORF Vector (Rat) (pORF) |
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ORF075399 | ABM | 1.0 ug DNA | EUR 607.2 |
Rlim ORF Vector (Mouse) (pORF) |
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ORF056109 | ABM | 1.0 ug DNA | EUR 607.2 |
RLIM ORF Vector (Human) (pORF) |
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ORF008833 | ABM | 1.0 ug DNA | EUR 114 |
Ring Finger Protein, Lim Domain Interacting (RLIM) Antibody |
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20-abx115301 | Abbexa |
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Ring Finger Protein, LIM Domain Interacting (RLIM) Antibody |
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abx237320-100ug | Abbexa | 100 ug | EUR 610.8 |
Rlim sgRNA CRISPR Lentivector set (Rat) |
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K6457601 | ABM | 3 x 1.0 ug | EUR 406.8 |
Rlim sgRNA CRISPR Lentivector set (Mouse) |
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K5023801 | ABM | 3 x 1.0 ug | EUR 406.8 |
RLIM sgRNA CRISPR Lentivector set (Human) |
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K1827101 | ABM | 3 x 1.0 ug | EUR 406.8 |
Rlim sgRNA CRISPR Lentivector (Rat) (Target 1) |
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K6457602 | ABM | 1.0 ug DNA | EUR 184.8 |
Rlim sgRNA CRISPR Lentivector (Rat) (Target 2) |
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K6457603 | ABM | 1.0 ug DNA | EUR 184.8 |
Rlim sgRNA CRISPR Lentivector (Rat) (Target 3) |
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K6457604 | ABM | 1.0 ug DNA | EUR 184.8 |
Rlim sgRNA CRISPR Lentivector (Mouse) (Target 1) |
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K5023802 | ABM | 1.0 ug DNA | EUR 184.8 |
Rlim sgRNA CRISPR Lentivector (Mouse) (Target 2) |
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K5023803 | ABM | 1.0 ug DNA | EUR 184.8 |
Rlim sgRNA CRISPR Lentivector (Mouse) (Target 3) |
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K5023804 | ABM | 1.0 ug DNA | EUR 184.8 |
RLIM sgRNA CRISPR Lentivector (Human) (Target 1) |
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K1827102 | ABM | 1.0 ug DNA | EUR 184.8 |
RLIM sgRNA CRISPR Lentivector (Human) (Target 2) |
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K1827103 | ABM | 1.0 ug DNA | EUR 184.8 |
RLIM sgRNA CRISPR Lentivector (Human) (Target 3) |
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K1827104 | ABM | 1.0 ug DNA | EUR 184.8 |
RLIM Protein Vector (Human) (pPB-C-His) |
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PV035329 | ABM | 500 ng | EUR 394.8 |
RLIM Protein Vector (Human) (pPB-N-His) |
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PV035330 | ABM | 500 ng | EUR 394.8 |
RLIM Protein Vector (Human) (pPM-C-HA) |
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PV035331 | ABM | 500 ng | EUR 394.8 |
RLIM Protein Vector (Human) (pPM-C-His) |
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PV035332 | ABM | 500 ng | EUR 394.8 |
RLIM Protein Vector (Rat) (pPB-C-His) |
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PV301594 | ABM | 500 ng | EUR 723.6 |
RLIM Protein Vector (Rat) (pPB-N-His) |
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PV301595 | ABM | 500 ng | EUR 723.6 |
RLIM Protein Vector (Rat) (pPM-C-HA) |
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PV301596 | ABM | 500 ng | EUR 723.6 |
RLIM Protein Vector (Rat) (pPM-C-His) |
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PV301597 | ABM | 500 ng | EUR 723.6 |
RLIM Protein Vector (Mouse) (pPB-C-His) |
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PV224434 | ABM | 500 ng | EUR 723.6 |
RLIM Protein Vector (Mouse) (pPB-N-His) |
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PV224435 | ABM | 500 ng | EUR 723.6 |
RLIM Protein Vector (Mouse) (pPM-C-HA) |
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PV224436 | ABM | 500 ng | EUR 723.6 |
RLIM Protein Vector (Mouse) (pPM-C-His) |
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PV224437 | ABM | 500 ng | EUR 723.6 |
Rlim 3'UTR Luciferase Stable Cell Line |
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TU219467 | ABM | 1.0 ml | Ask for price |
Rlim 3'UTR GFP Stable Cell Line |
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TU167914 | ABM | 1.0 ml | Ask for price |
Rlim 3'UTR GFP Stable Cell Line |
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TU269467 | ABM | 1.0 ml | Ask for price |
Rlim 3'UTR Luciferase Stable Cell Line |
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TU117914 | ABM | 1.0 ml | Ask for price |
RLIM 3'UTR GFP Stable Cell Line |
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TU069947 | ABM | 1.0 ml | EUR 5540.4 |
RLIM 3'UTR Luciferase Stable Cell Line |
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TU019947 | ABM | 1.0 ml | EUR 5540.4 |
Human Ring Finger Protein, LIM Domain Interacting (RLIM) ELISA Kit |
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abx382827-96tests | Abbexa | 96 tests | EUR 1093.2 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
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K6457605 | ABM | 3 x 1.0 ug | EUR 451.2 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
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K5023805 | ABM | 3 x 1.0 ug | EUR 451.2 |
RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
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K1827105 | ABM | 3 x 1.0 ug | EUR 451.2 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
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K6457606 | ABM | 1.0 ug DNA | EUR 200.4 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2) |
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K6457607 | ABM | 1.0 ug DNA | EUR 200.4 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3) |
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K6457608 | ABM | 1.0 ug DNA | EUR 200.4 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
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K5023806 | ABM | 1.0 ug DNA | EUR 200.4 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
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K5023807 | ABM | 1.0 ug DNA | EUR 200.4 |
Rlim sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
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K5023808 | ABM | 1.0 ug DNA | EUR 200.4 |
RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
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K1827106 | ABM | 1.0 ug DNA | EUR 200.4 |
RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
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K1827107 | ABM | 1.0 ug DNA | EUR 200.4 |
RLIM sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
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K1827108 | ABM | 1.0 ug DNA | EUR 200.4 |
Positive control tissue section for each individua |
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Control-Slides-for-each-antibody | Innovex | Set of 25 | EUR 355 |
Description: Positive control tissue section for each individual antibody; Based on availability; INQUIRE |
Anti-Anti-SEPT6 antibody antibody |
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STJ11100949 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. |
Anti-Anti-SEPT9 Antibody antibody |
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STJ111369 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
Anti-Anti-SEPT11 Antibody antibody |
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STJ111530 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT4 Antibody antibody |
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STJ112276 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
Anti-Anti-MARCH9 Antibody antibody |
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STJ112609 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT2 Antibody antibody |
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STJ25475 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT5 Antibody antibody |
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STJ25477 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
Anti-Anti-SEPT8 Antibody antibody |
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STJ25479 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Anti-Anti-SEPT2 Antibody antibody |
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STJ28365 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT7 Antibody antibody |
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STJ28963 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
Anti-Anti-SEPT1 antibody antibody |
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STJ119580 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] |
Anti-Anti-SEPT12 Antibody antibody |
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STJ117759 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. |
Anti-Anti-MARCH6 Antibody antibody |
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STJ118549 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-MARCH6 Antibody antibody |
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STJ118550 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-MARCH7 Antibody antibody |
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STJ118752 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT3 Antibody antibody |
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STJ118990 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT11 Antibody antibody |
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STJ113941 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT11 Antibody antibody |
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STJ114081 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT5 Antibody antibody |
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STJ114819 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
Anti-Anti-MARCH8 Antibody antibody |
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STJ114828 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT7 Antibody antibody |
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STJ116214 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
Anti-Anti-SEPT8 Antibody antibody |
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STJ117206 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Anti-Anti-DDB1 Antibody |
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A00333 | BosterBio | 100uL | EUR 546 |
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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AEA465Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6777.36 |
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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AEA465Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 663.31 |
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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AEA465Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 896.16 |
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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AEA465Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3672.72 |
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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4-AEA465Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody) |
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ELK8071 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Anti-H4K20me1 Antibody |
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CI1005 | BosterBio | 100ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
Anti-H4K20me3 Antibody |
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CI1011 | BosterBio | 100ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
Anti-TIP5 Antibody |
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CI1016 | BosterBio | 100ul | EUR 589.2 |
Description: Rabbit Polyclonal TIP5 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human, Mouse. |
Anti-H4K8ac Antibody |
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CI1021 | BosterBio | 100ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
Anti-MYH11 Antibody |
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CI1028 | BosterBio | 100ul | EUR 589.2 |
Description: Rabbit Polyclonal MYH11 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human. |
Anti-Ski3 Antibody |
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CI1031 | BosterBio | 150ug/50ul | EUR 589.2 |
Description: Rabbit Polyclonal Ski3 Antibody. Validated in ChIP, ChIP-qPCR, IF, IHC, WB and tested in Human. |
Anti-Ski8 Antibody |
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CI1032 | BosterBio | 150ug/60ul | EUR 589.2 |
Description: Rabbit Polyclonal Ski8 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Drosophila, Human. |
Anti-H4K5,8,12ac Antibody |
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CI1033 | BosterBio | 50ug/66ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K5,8,12ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse. |
Anti-H4K5,8,12,16ac Antibody |
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CI1035 | BosterBio | 50ug/66ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K5,8,12,16ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse. |
Anti-H4K5ac Antibody |
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CI1036 | BosterBio | 50ug/28ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human, Mouse. |
Anti-H4K20me1 Antibody |
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CI1039 | BosterBio | 50ug/25ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
Anti-MeCP2 Antibody |
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CI1047 | BosterBio | 50ug/42ul | EUR 589.2 |
Description: Rabbit Polyclonal MeCP2 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
Anti-H4K20me3 Antibody |
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CI1050 | BosterBio | 50ug/47ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse. |
Anti-H3K27me3 Antibody |
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CI1056 | BosterBio | 50ug/34ul | EUR 589.2 |
Description: Rabbit Polyclonal H3K27me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Arabidopsis, Drosophila, Human, Mouse, Rat, Schistosoma, Zebrafish. |
Anti-MBD1 Antibody |
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CI1058 | BosterBio | 50ug/72ul | EUR 589.2 |
Description: Rabbit Polyclonal MBD1 Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human, Mouse. |
Anti-p53 Antibody |
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CI1060 | BosterBio | 50ug/50ul | EUR 589.2 |
Description: Rabbit Polyclonal p53 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IHC, WB and tested in Human. |
Anti-H4K8ac Antibody |
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CI1066 | BosterBio | 50ug/41ul | EUR 589.2 |
Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse. |
Anti-H4pan Antibody |
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CI1069 | BosterBio | 50ug/44ul | EUR 589.2 |
Description: Rabbit Polyclonal H4pan Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human. |
Anti-H2AK5ac Antibody |
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CI1078 | BosterBio | 50ug/ 54ul | EUR 589.2 |
Description: Rabbit Polyclonal H2AK5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human. |
Antibody Anti-cKit |
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CKITACPO | ImmunoStep | 0,1 mg | EUR 379.8 |
anti- LIN28B antibody |
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FNab04785 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LIN28B |
anti- LIN41 antibody |
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FNab04787 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LIN41 |
anti- LIN7A antibody |
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FNab04788 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against LIN7A |
anti- LIN7B antibody |
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FNab04789 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LIN7B |
anti- LIN7C antibody |
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FNab04790 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LIN7C |
anti- LIN9 antibody |
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FNab04791 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LIN9 |
anti- LINGO1 antibody |
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FNab04792 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LINGO1 |
anti- LIPA antibody |
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FNab04793 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LIPA |
anti- LIPC antibody |
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FNab04794 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LIPC |
anti- LIPH antibody |
|||
FNab04795 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LIPH |
anti- LIPI antibody |
|||
FNab04796 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against LIPI |
anti- LITAF antibody |
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FNab04798 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LITAF |
anti- LKB1 antibody |
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FNab04802 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LKB1 |
anti- LMAN1 antibody |
|||
FNab04803 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LMAN1 |
anti- LMBR1L antibody |
|||
FNab04804 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LMBR1L |
anti- LMF1 antibody |
|||
FNab04805 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LMF1 |
anti- LMF2 antibody |
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FNab04806 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LMF2 |
anti- LMNB2 antibody |
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FNab04807 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LMNB2 |
anti- LMOD1 antibody |
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FNab04808 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LMOD1 |
anti- LMOD3 antibody |
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FNab04809 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LMOD3 |
anti- LMP2 antibody |
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FNab04810 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LMP2 |
anti- LMP7 antibody |
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FNab04811 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LMP7 |
anti- LMX1B antibody |
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FNab04812 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against LMX1B |
anti- LNPEP antibody |
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FNab04813 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against LNPEP |
anti- LNX1 antibody |
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FNab04814 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LNX1 |
Acyclovir-induced neurotoxicity with a constructive cerebrospinal fluid varicella zoster PCR outcome making a administration dilemma: a case report
Background: Varicella zoster virus central nervous system infections can current as aseptic meningitis, encephalitis, myelitis, and vasculopathy. Analysis is predicated on identification of varicella zoster virus deoxyribonucleic acid (DNA) within the cerebrospinal fluid by polymerase chain response. Remedy for these infections is acyclovir or valacyclovir.
Nonetheless, acyclovir can have neurotoxic results that may mimic the presentation of varicella zoster virus central nervous system illness. We current a uncommon presentation of a affected person who had acyclovir-induced neurotoxicity who additionally had a false-positive cerebrospinal fluid varicella zoster virus polymerase chain response outcome, making a administration dilemma.
We evaluate the scientific traits of acyclovir-induced neurotoxicity. As well as, we current the diagnostic traits of the cerebrospinal fluid viral polymerase chain response and different strategies to diagnose central nervous system varicella zoster virus illness.
Case presentation: A 68-year-old Hispanic man with end-stage renal illness was recognized with cutaneous zoster at an outdoor facility and was began on acyclovir four days previous to admission. His household famous worsening confusion, agitation, speech issue, and hallucinations, main them to carry him to the emergency division.
His cerebrospinal fluid varicella zoster virus polymerase
chain response outcome was constructive, indicating the presence of varicella zoster virus deoxyribonucleic acid within the cerebrospinal fluid; nonetheless, he didn’t have cerebrospinal fluid pleocytosis typical of varicella zoster virus meningoencephalitis.
Pharmacy information from the surface hospital revealed supratherapeutic acyclovir dosing. This led to a diagnostic dilemma over whether or not this affected person had varicella zoster virus encephalitis or acyclovir-induced neurotoxicity. Acyclovir was discontinued, and the affected person underwent two periods of hemodialysis to take away acyclovir, which led to a full neurologic restoration.
Conclusions: Varicella zoster virus encephalitis and acyclovir-induced neurotoxicity can have comparable displays. Varicella zoster virus deoxyribonucleic acid will be current within the cerebrospinal fluid throughout lively cutaneous zoster within the absence of central nervous system illness. If concern for central nervous system varicella zoster virus illness stays excessive, further testing with cerebrospinal fluid serology will be carried out.
In contrast with central nervous system varicella zoster virus illness, acyclovir-induced neurotoxicity has a extra predictable scientific decision as soon as drug remedy is discontinued or the affected person undergoes hemodialysis, which might support in making the prognosis. Clinicians ought to pay attention to this uncommon and harmful complication of acyclovir.
As well as, clinicians ought to have an understanding of the diagnostic limitations of cerebrospinal fluid viral polymerase chain response and have different approaches out there to diagnose central nervous system varicella zoster virus illness when it’s suspected.
SFT2D3 Blocking Peptide |
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DF10009-BP | Affbiotech | 1mg | EUR 234 |
SEC22B Blocking Peptide |
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DF10010-BP | Affbiotech | 1mg | EUR 234 |
TMEM37 Blocking Peptide |
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DF10011-BP | Affbiotech | 1mg | EUR 234 |
CACNA1D Blocking Peptide |
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DF10012-BP | Affbiotech | 1mg | EUR 234 |
CACNA1E Blocking Peptide |
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DF10013-BP | Affbiotech | 1mg | EUR 234 |
CACNA1G Blocking Peptide |
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DF10014-BP | Affbiotech | 1mg | EUR 234 |
ZNHIT1 Blocking Peptide |
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DF10015-BP | Affbiotech | 1mg | EUR 234 |
ZFHX4 Blocking Peptide |
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DF10016-BP | Affbiotech | 1mg | EUR 234 |
ZNF295 Blocking Peptide |
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DF10017-BP | Affbiotech | 1mg | EUR 234 |
ZNF462 Blocking Peptide |
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DF10018-BP | Affbiotech | 1mg | EUR 234 |
ZNF600 Blocking Peptide |
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DF10019-BP | Affbiotech | 1mg | EUR 234 |
SLC30A2 Blocking Peptide |
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DF10020-BP | Affbiotech | 1mg | EUR 234 |
SLC39A10 Blocking Peptide |
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DF10021-BP | Affbiotech | 1mg | EUR 234 |
ZP2 Blocking Peptide |
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DF10022-BP | Affbiotech | 1mg | EUR 234 |
CD164L2 Blocking Peptide |
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DF10023-BP | Affbiotech | 1mg | EUR 234 |
CC50A Blocking Peptide |
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DF10024-BP | Affbiotech | 1mg | EUR 234 |
CCNI Blocking Peptide |
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DF10025-BP | Affbiotech | 1mg | EUR 234 |
CD2L5 Blocking Peptide |
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DF10026-BP | Affbiotech | 1mg | EUR 234 |
CD2L6 Blocking Peptide |
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DF10027-BP | Affbiotech | 1mg | EUR 234 |
CD2L7 Blocking Peptide |
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DF10028-BP | Affbiotech | 1mg | EUR 234 |
MAGA2 Blocking Peptide |
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DF10029-BP | Affbiotech | 1mg | EUR 234 |
MAGA3 Blocking Peptide |
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DF10030-BP | Affbiotech | 1mg | EUR 234 |
MAGA6 Blocking Peptide |
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DF10031-BP | Affbiotech | 1mg | EUR 234 |
MAGA8 Blocking Peptide |
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DF10032-BP | Affbiotech | 1mg | EUR 234 |
MAGAB Blocking Peptide |
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DF10033-BP | Affbiotech | 1mg | EUR 234 |
MAGAC Blocking Peptide |
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DF10034-BP | Affbiotech | 1mg | EUR 234 |
MAGB2 Blocking Peptide |
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DF10035-BP | Affbiotech | 1mg | EUR 234 |
MAGB3 Blocking Peptide |
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DF10036-BP | Affbiotech | 1mg | EUR 234 |
MAGB6 Blocking Peptide |
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DF10037-BP | Affbiotech | 1mg | EUR 234 |
MAGBA Blocking Peptide |
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DF10038-BP | Affbiotech | 1mg | EUR 234 |
MAGBI Blocking Peptide |
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DF10039-BP | Affbiotech | 1mg | EUR 234 |
MAGD2 Blocking Peptide |
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DF10040-BP | Affbiotech | 1mg | EUR 234 |
MAGE2 Blocking Peptide |
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DF10041-BP | Affbiotech | 1mg | EUR 234 |
MAGG1 Blocking Peptide |
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DF10042-BP | Affbiotech | 1mg | EUR 234 |
MAGH1 Blocking Peptide |
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DF10043-BP | Affbiotech | 1mg | EUR 234 |
KITH_HHV1E Blocking Peptide |
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DF10044-BP | Affbiotech | 1mg | EUR 234 |
CNBP Blocking Peptide |
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DF10045-BP | Affbiotech | 1mg | EUR 234 |
HEN2 Blocking Peptide |
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DF10046-BP | Affbiotech | 1mg | EUR 234 |
ATOH8 Blocking Peptide |
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DF10047-BP | Affbiotech | 1mg | EUR 234 |
AKAP4 Blocking Peptide |
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DF10048-BP | Affbiotech | 1mg | EUR 234 |
GFI1B Blocking Peptide |
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DF10049-BP | Affbiotech | 1mg | EUR 234 |
DMRTA1 Blocking Peptide |
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DF10050-BP | Affbiotech | 1mg | EUR 234 |
ZNF25 Blocking Peptide |
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DF10051-BP | Affbiotech | 1mg | EUR 234 |
TSH3 Blocking Peptide |
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DF10052-BP | Affbiotech | 1mg | EUR 234 |
LARP2 Blocking Peptide |
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DF10053-BP | Affbiotech | 1mg | EUR 234 |
UL97 Blocking Peptide |
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DF10054-BP | Affbiotech | 1mg | EUR 234 |
TRIM68 Blocking Peptide |
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DF10055-BP | Affbiotech | 1mg | EUR 234 |
TCF2 Blocking Peptide |
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DF10056-BP | Affbiotech | 1mg | EUR 234 |
ZNF839 Blocking Peptide |
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DF10057-BP | Affbiotech | 1mg | EUR 234 |
PTRF Blocking Peptide |
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DF10058-BP | Affbiotech | 1mg | EUR 234 |
CYFIP1 Blocking Peptide |
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DF10059-BP | Affbiotech | 1mg | EUR 234 |
TRMT11 Blocking Peptide |
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DF10060-BP | Affbiotech | 1mg | EUR 234 |
ZNF227 Blocking Peptide |
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DF10061-BP | Affbiotech | 1mg | EUR 234 |
DMRTC2 Blocking Peptide |
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DF10062-BP | Affbiotech | 1mg | EUR 234 |
YAF2 Blocking Peptide |
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DF10063-BP | Affbiotech | 1mg | EUR 234 |
ASPM Blocking Peptide |
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DF10064-BP | Affbiotech | 1mg | EUR 234 |
ZNF786 Blocking Peptide |
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DF10065-BP | Affbiotech | 1mg | EUR 234 |
C16orf44 Blocking Peptide |
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DF10066-BP | Affbiotech | 1mg | EUR 234 |
LZTR1 Blocking Peptide |
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DF10067-BP | Affbiotech | 1mg | EUR 234 |
ZNF441 Blocking Peptide |
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DF10068-BP | Affbiotech | 1mg | EUR 234 |
TUSC4 Blocking Peptide |
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DF10069-BP | Affbiotech | 1mg | EUR 234 |
TP73 Blocking Peptide |
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DF10070-BP | Affbiotech | 1mg | EUR 234 |
MINA Blocking Peptide |
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DF10071-BP | Affbiotech | 1mg | EUR 234 |
CI098 Blocking Peptide |
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DF10072-BP | Affbiotech | 1mg | EUR 234 |
DUX5 Blocking Peptide |
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DF10073-BP | Affbiotech | 1mg | EUR 234 |
CIC Blocking Peptide |
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DF10074-BP | Affbiotech | 1mg | EUR 234 |
NEB2 Blocking Peptide |
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DF10075-BP | Affbiotech | 1mg | EUR 234 |
MYCBP Blocking Peptide |
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DF10076-BP | Affbiotech | 1mg | EUR 234 |
ZNF577 Blocking Peptide |
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DF10078-BP | Affbiotech | 1mg | EUR 234 |
HIPK3 Blocking Peptide |
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DF10079-BP | Affbiotech | 1mg | EUR 234 |
POLM Blocking Peptide |
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DF10080-BP | Affbiotech | 1mg | EUR 234 |
NOLA1 Blocking Peptide |
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DF10081-BP | Affbiotech | 1mg | EUR 234 |
TF2L1 Blocking Peptide |
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DF10082-BP | Affbiotech | 1mg | EUR 234 |
VPS54 Blocking Peptide |
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DF10083-BP | Affbiotech | 1mg | EUR 234 |
RHCG Blocking Peptide |
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DF10084-BP | Affbiotech | 1mg | EUR 234 |
RTDR1 Blocking Peptide |
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DF10086-BP | Affbiotech | 1mg | EUR 234 |
JDP2 Blocking Peptide |
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DF10087-BP | Affbiotech | 1mg | EUR 234 |
CDYL1 Blocking Peptide |
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DF10088-BP | Affbiotech | 1mg | EUR 234 |
DUET Blocking Peptide |
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DF10089-BP | Affbiotech | 1mg | EUR 234 |
CDY1 Blocking Peptide |
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DF10090-BP | Affbiotech | 1mg | EUR 234 |
CCBE1 Blocking Peptide |
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DF10092-BP | Affbiotech | 1mg | EUR 234 |
COX7B Blocking Peptide |
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DF10093-BP | Affbiotech | 1mg | EUR 234 |
COX7A2L Blocking Peptide |
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DF10094-BP | Affbiotech | 1mg | EUR 234 |
COX82 Blocking Peptide |
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DF10095-BP | Affbiotech | 1mg | EUR 234 |
COX6A2 Blocking Peptide |
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DF10096-BP | Affbiotech | 1mg | EUR 234 |
COX6B2 Blocking Peptide |
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DF10097-BP | Affbiotech | 1mg | EUR 234 |
COX7A1 Blocking Peptide |
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DF10098-BP | Affbiotech | 1mg | EUR 234 |
CYBA Blocking Peptide |
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DF10099-BP | Affbiotech | 1mg | EUR 234 |
DEDD Blocking Peptide |
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DF10100-BP | Affbiotech | 1mg | EUR 234 |
DNAJB2 Blocking Peptide |
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DF10101-BP | Affbiotech | 1mg | EUR 234 |
EMID2 Blocking Peptide |
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DF10102-BP | Affbiotech | 1mg | EUR 234 |
FBF1 Blocking Peptide |
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DF10103-BP | Affbiotech | 1mg | EUR 234 |
GRIK5 Blocking Peptide |
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DF10104-BP | Affbiotech | 1mg | EUR 234 |
GRIP2 Blocking Peptide |
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DF10105-BP | Affbiotech | 1mg | EUR 234 |
IL20L2 Blocking Peptide |
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DF10106-BP | Affbiotech | 1mg | EUR 234 |
IL22RA2 Blocking Peptide |
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DF10107-BP | Affbiotech | 1mg | EUR 234 |
IL28RA Blocking Peptide |
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DF10108-BP | Affbiotech | 1mg | EUR 234 |
IFNW1 Blocking Peptide |
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DF10109-BP | Affbiotech | 1mg | EUR 234 |
IGFL2 Blocking Peptide |
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DF10110-BP | Affbiotech | 1mg | EUR 234 |
IGFL4 Blocking Peptide |
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DF10111-BP | Affbiotech | 1mg | EUR 234 |
IL1F7 Blocking Peptide |
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DF10112-BP | Affbiotech | 1mg | EUR 234 |
IL1F9 Blocking Peptide |
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DF10113-BP | Affbiotech | 1mg | EUR 234 |
IL31R Blocking Peptide |
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DF10114-BP | Affbiotech | 1mg | EUR 234 |
IFI6 Blocking Peptide |
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DF10115-BP | Affbiotech | 1mg | EUR 234 |
KRT84 Blocking Peptide |
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DF10116-BP | Affbiotech | 1mg | EUR 234 |
SETMAR Blocking Peptide |
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DF10118-BP | Affbiotech | 1mg | EUR 234 |
CCNB3 Blocking Peptide |
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DF10120-BP | Affbiotech | 1mg | EUR 234 |
MCM8 Blocking Peptide |
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DF10122-BP | Affbiotech | 1mg | EUR 234 |
STRN Blocking Peptide |
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DF10123-BP | Affbiotech | 1mg | EUR 234 |
KLF17 Blocking Peptide |
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DF10124-BP | Affbiotech | 1mg | EUR 234 |
ORC3 Blocking Peptide |
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DF10126-BP | Affbiotech | 1mg | EUR 234 |
PIK3C2G Blocking Peptide |
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DF10131-BP | Affbiotech | 1mg | EUR 234 |
NPR1 Blocking Peptide |
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DF10132-BP | Affbiotech | 1mg | EUR 234 |