juni 10, 2023

Human IMPDH Inhibitor Screening Assay

Human IMPDH Inhibitor Screening Assay 

To Order Contact us: bjorn@lembcke.dk

NAMPT Inhibitor Screening Assay Kit
71276-2 384 rxns.
EUR 930
Description: The NAMPT Inhibitor Screening Assay Kit is designed to measure NAMPT activity for screening and profiling applications. The key to the assay is a coupled reaction including NMNAT and ADH. NAMPT converts nicotinamide substrate to nicotinamide mononucleotide (NMN) via PRPP. NMNAT subsequently converts NMN to NAD+ , which is reduced by ADH to NADH, permitting detection of the fluorescent NADH signal.

MAT2A Inhibitor Screening Assay Kit
71402 384 rxns.
EUR 1275
Description: The MAT2a Inhibitor Screening Assay Kit is designed to measure MAT2A activity for screening and profiling applications. The MAT2A assay kit comes in a convenient 384-well format, with purified recombinant MAT2A enzyme, L-Methionine, ATP, MAT2A assay buffer, and Colorimetric detection reagent for 384 enzyme reactions.

ARG2 Inhibitor Screening Assay Kit
72043-1 96 rxns.
EUR 765
Description: The ARG2 Inhibitor Screening Assay Kit is designed to measure ARG2 enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 100 reactions. The ARG2 Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing thioarginine substrate. After a room temperature incubation, activity is determined by measuring the absorption of reaction product at λ=410-415 nm.

ARG2 Inhibitor Screening Assay Kit
72043-2 384 rxns.
EUR 1130
Description: The ARG2 Inhibitor Screening Assay Kit is designed to measure ARG2 enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 400 reactions. The ARG2 Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing thioarginine substrate. After a room temperature incubation, activity is determined by measuring the absorption of reaction product at λ=410-415 nm.

ARG1 Inhibitor Screening Assay Kit
72048-1 96 rxns.
EUR 845
Description: The ARG1 Inhibitor Screening Assay Kit is designed to measure ARG1 enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 100 reactions. The ARG1 Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing thioarginine substrate. After a room temperature incubation, activity is determined by measuring the absorption of reaction product at λ=410-415 nm.

ARG1 Inhibitor Screening Assay Kit
72048-2 384 rxns.
EUR 1245
Description: The ARG1 Inhibitor Screening Assay Kit is designed to measure ARG1 enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 400 reactions. The ARG1 Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing thioarginine substrate. After a room temperature incubation, activity is determined by measuring the absorption of reaction product at λ=410-415 nm.

TPH1 Inhibitor Screening Assay Kit
72053 96 rxns.
EUR 790
Description: The TPH1 Assay Kit is designed to measure TPH1 enzyme inhibition in a 96 reaction format. This fluorescence-based assay kit is especially suitable for high throughput screening applications. The procedure is quick, straightforward, and simple - just mix two solutions, incubate, add quenching solution, and measure the fluorescence.

TPH2 Inhibitor Screening Assay Kit
72054 96 rxns.
EUR 790
Description: The TPH2 Assay Kit is designed to measure TPH2 enzyme inhibition in a 96 reaction format. This fluorescence-based assay kit is especially suitable for high throughput screening applications. The procedure is quick, straightforward, and simple - just mix two solutions, incubate, add quenching solution, and measure the fluorescence.

CD73 Inhibitor Screening Assay Kit
72055 96 rxns.
EUR 935
Description: The CD73 Inhibitor Screening Assay Kit is designed to measure CD73 activity_x000D_for screening and profiling applications. The CD73 assay kit comes in a convenient 96-well_x000D_format, with purified recombinant CD73 enzyme, AMP, CD73 assay buffer, and Colorimetric_x000D_detection reagent for 100 enzyme reactions.

TPH1 Inhibitor Screening Assay Kit
72056 384 rxns.
EUR 1130
Description: The TPH1 Assay Kit is designed to measure TPH1 enzyme inhibition in a 384 reaction format. This fluorescence-based assay kit is especially suitable for high throughput screening applications. The procedure is quick, straightforward, and simple - just mix two solutions, incubate, add quenching solution, and measure the fluorescence.

TPH2 Inhibitor Screening Assay Kit
72057 384 rxns.
EUR 1130
Description: The TPH2 Assay Kit is designed to measure TPH2 enzyme inhibition in a 384 reaction format. This fluorescence-based assay kit is especially suitable for high throughput screening applications. The procedure is quick, straightforward, and simple - just mix two solutions, incubate, add quenching solution, and measure the fluorescence.

CD73 Inhibitor Screening Assay Kit
72058 384 rxns.
EUR 1245
Description: The CD73 Inhibitor Screening Assay Kit is designed to measure CD73 activity_x000D_for screening and profiling applications. The CD73 assay kit comes in a convenient 384-well_x000D_format, with purified recombinant CD73 enzyme, AMP, CD73 assay buffer, and Colorimetric_x000D_detection reagent for 384 enzyme reactions.

CBX1 Inhibitor Screening Assay Kit
79052 384 rxns.
EUR 535
Description: The CBX1 Inhibitor Screening Assay Kit is designed to measure the inhibition of CBX1 binding to its substrate. The kit comes in a convenient AlphaLISA® format, with enough biotinylated peptide substrate, assay buffer, detection buffer and purified GST-tagged CBX1 chromodomain to perform a total of 384 enzyme reactions. The key to the kit is the specific binding of the CBX1 chromodomain to the methylated-peptide substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing CBX1 and an inhibitor of choice is incubated with the biotinylated substrate for one hour. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

USP7 Inhibitor Screening Assay Kit
79256 96 rxns.
EUR 820
Description: The USP7 Inhibitor Screening Assay Kit is designed to measure USP7 activity for screening and profiling applications. The USP7 Inhibitor Screening Assay Kit comes in a convenient format, with a 96-well plate, fluorogenic, ubiquitinated substrate, assay buffer, and purified USP7 enzyme for 96 enzyme reactions. USP7 is incubated with a sample containing assay buffer and Ub-AMC Substrate, and then the plate is read, measuring fluorescence using a fluorescence reader.

CD39 Inhibitor Screening Assay Kit
79278 96 rxns.
EUR 890
Description: The CD39 Inhibitor Screening Assay Kit is designed to measure CD39 activity for screening and profiling applications. The CD39 assay kit comes in a convenient 96-well format, with purified recombinant CD39 enzyme, ATP, CD39 assay buffer, and Colorimetric detection reagent for 96 enzyme reactions. In addition, the kit includes the CD39 inhibitor POM-1 for use as an inhibitor control.

KMO Inhibitor Screening Assay Kit
79513-1 96 rxns.
EUR 790
Description: The Kynurenine 3-Monooxygenase (KMO) Inhibitor Screening Assay Kit is designed to measure human KMO enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 400 reactions. The KMO Inhibitor Screening Assay Kit is simple to use. Recombinant hKMO is mixed with inhibitors and the reaction is initiated through addition of the substrates NADPH and L-Kynurenine. After a room temperature incubation, activity is determined by measuring the absorption of the reaction product at λ=412 nm. The UV absorption signal correlates with the amount of NADPH remaining in the reaction.

KMO Inhibitor Screening Assay Kit
79513-2 384 rxns.
EUR 1070
Description: The Kynurenine 3-Monooxygenase (KMO) Inhibitor Screening Assay Kit is designed to measure human KMO enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 400 reactions. The KMO Inhibitor Screening Assay Kit is simple to use. Recombinant hKMO is mixed with inhibitors and the reaction is initiated through addition of the substrates NADPH and L-Kynurenine. After a room temperature incubation, activity is determined by measuring the absorption of the reaction product at λ=412 nm. The UV absorption signal correlates with the amount of NADPH remaining in the reaction.

Kynureninase Inhibitor Screening Assay Kit
79514 100 rxns.
EUR 830
Description: The Kynureninase (KYNU) Inhibitor Screening Assay Kit is designed to measure human KYNU enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 100 reactions. The KYNU Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are mixed and the reaction is initiated through addition of the substrate 3-hydroxy-DL-kynurenine (3-HK). After a room temperature incubation, activity is determined by measuring the fluorescence of the reaction product (ex. 315 nm, em. 415 nm).

GLS1 Inhibitor Screening Assay Kit
79596 96 rxns.
EUR 840
Description: The GLS1 Inhibitor Screening Assay Kit is designed to measure the hydrolase activity of GLS1 for screening and profiling applications.

ACE2 Inhibitor Screening Assay Kit
79923 96 rxns.
EUR 545
Description: The ACE2 Inhibitor Screening Assay Kit is designed to measure the exopeptidase activity of ACE2 for screening and profiling applications. 

GLS2 Inhibitor Screening Assay Kit
79925 96 rxns.
EUR 780
Description: The GLS2 Inhibitor Screening Assay Kit is designed to measure the hydrolase activity of GLS2 for screening and profiling applications.

UBE1 Inhibitor Screening Assay Kit
79957 96 rxns.
EUR 765
Description: UBE1 dysregulation has been linked to muscular atrophy, tumors, and cancer. The UBE1 Inhibitor Screening Assay Kit is designed to measure UBE1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. 

BRD1 Inhibitor Screening Assay Kit
32521 384 rxns.
EUR 510
Description: The BRD1 Inhibitor Screening Assay Kit is designed to measure the inhibition of BRD1 binding to its substrate. The key to the BRD1 Inhibitor Screening Assay Kit is the specific binding of the BRD1 bromodomain to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRD1 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

BAZ2B Inhibitor Screening Assay Kit
32600 384 rxns.
EUR 510
Description: The BAZ2B Inhibitor Screening Assay Kit is designed to measure the inhibition of BAZ2B binding to its substrate. The key to the BAZ2B Inhibitor Screening Assay Kit is the highly specific binding of the BAZ2B bromodomain to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BAZ2B and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

ATAD2A Inhibitor Screening Assay Kit
32601 384 rxns.
EUR 1025
Description: The ATAD2A Inhibitor Screening Assay Kit is designed to measure the inhibition of ATAD2A binding to its substrate. The key to the ATAD2A Inhibitor Screening Assay Kit is a specific binding of the ATAD2A bromodomain to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing ATAD2A and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

ATAD2B Inhibitor Screening Assay Kit
32605 384 rxns.
EUR 1025
Description: The ATAD2B Inhibitor Screening Assay Kit is designed to measure the inhibition of ATAD2B binding to its substrate. The key to the kit is the specific binding of the ATAD2B bromodomain to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing ATAD2B and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

TRIM24 Inhibitor Screening Assay Kit
32606 384 rxns.
EUR 1025
Description: The TRIM24 Inhibitor Screening Assay Kit is designed to measure the inhibition of TRIM24 binding to its substrate. The key to the TRIM24 Inhibitor Screening Assay Kit is the specific binding of the TRIM24 bromodomain to an acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing TRIM24 and an inhibitor of choice is incubated with the biotinylated substrate. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

CREBBP Inhibitor Screening Assay Kit
32607 384 rxns.
EUR 510
Description: The CREBBP Inhibitor Screening Assay Kit is designed to measure the inhibition of CREBBP binding to its substrate. The key to the CREBBP Inhibitor Screening Assay Kit is a specific binding of the CREBBP bromodomain to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing CREBBP and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

BRPF3 Inhibitor Screening Assay Kit
32608 384 rxns.
EUR 1025
Description: The BRPF3 Inhibitor Screening Assay Kit is designed to measure the inhibition of BRPF3 binding to its substrate. The key to the BRPF3 Inhibitor Screening Assay Kit is the specific binding of the BRPF3 bromodomain to an acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRPF3 and an inhibitor of choice is incubated with the biotinylated substrate. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts

SMARCA2 Inhibitor Screening Assay Kit
32610 384 rxns.
EUR 510
Description: The SMARCA2 Inhibitor Screening Assay Kit is designed to measure the inhibition of SMARCA2 binding to its substrate. The key to the SMARCA2 Inhibitor Screening Assay Kit is the specific binding of the SMARCA2 bromodomain to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing SMARCA2 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

CECR2 Inhibitor Screening Assay Kit
32611 384 rxns.
EUR 1025
Description: The CECR2 Inhibitor Screening Assay Kit is designed to measure the inhibition of CECR2 binding to its substrate. The key to the CECR2 Inhibitor Screening Assay Kit is the highly specific binding of the CECR2 bromodomain to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing CECR2 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

Human IDO1 Inhibitor Screening Assay Kit
72021 96 rxns.
EUR 780
Description: The IDO1 Inhibitor Screening Assay Kit is designed to measure IDO1 enzyme inhibition. The IDO1 Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing L-Trp substrate. After a room temperature incubation, activity is determined by measuring the absorption of reaction product at λ=321 nm.

Human IDO2 Inhibitor Screening Assay Kit
72022 96 rxns.
EUR 900
Description: The IDO2 Inhibitor Screening Assay Kit is designed to measure IDO2 enzyme inhibition. The IDO2 Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing L-Trp substrate.

Human TDO Inhibitor Screening Assay Kit
72023 96 rxns.
EUR 745
Description: The TDO Inhibitor Screening Assay Kit is designed to measure TDO enzyme inhibition. The kit comes in a convenient format, with enough reaction solution and enzyme to perform a total of 100 reactions. The TDO Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing L-Trp substrate. After a room temperature incubation activity is measured by measuring the absorption of reaction product at λ = 320-325 nm.

Human IDO1 Inhibitor Screening Assay Kit (384)
72034 384 rxns.
EUR 1070
Description: The IDO1 Inhibitor Screening Assay Kit is designed to measure IDO1 enzyme inhibition. The IDO1 Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing L-Trp substrate. After a room temperature incubation, activity is determined by measuring the absorption of reaction product at  =320-325 nm.

Human TDO Inhibitor Screening Assay Kit (384)
72036 384 rxns.
EUR 1070
Description: The TDO Inhibitor Screening Assay Kit is designed to measure TDO enzyme inhibition. The TDO Inhibitor Screening Assay Kit is simple to use. Inhibitor and enzyme are added to a sample containing L-Trp substrate. After a room temperature incubation, activity is measured by measuring the absorption of reaction product at  = 320-325 nm.

Human IDO1 Fluorogenic Inhibitor Screening Assay Kit
72037 96 rxns.
EUR 780
Description: The IDO1 Fluorogenic Inhibitor Screening Assay Kit is designed to measure enzyme inhibition of indoleamine 2,3-dioxygenase 1 (IDO1). The IDO1 Fluorogenic Inhibitor Screening Assay Kit is simple to use and detects fluorescence at long wavelengths, which minimizes potential errors due to compound interference. In the assay, the inhibitor and enzyme are added to a sample containing L-Trp substrate. After a 1 hourincubation at room temperature, the fluorescence solution is added and incubated at 37°C for four hours. Activity is measured by reading sample fluorescence at λ=510 nm following excitation of the reaction product at λ=400 nm.

Human TDO Fluorogenic Inhibitor Screening Assay Kit
72039 96 rxns.
EUR 745
Description: The TDO Fluorogenic Inhibitor Screening Assay Kit is designed to measure enzyme inhibition of tryptophan 2,3-dioxygenase (TDO). The TDO Fluorogenic Inhibitor Screening Assay Kit is simple to use and detects fluorescence at long wavelengths, which minimizes potential errors due to compound interference. In the assay, the inhibitor and enzyme are added to a sample containing L-Trp substrate. After a 1 hour incubation at room temperature, the fluorescence solution is added and incubated at 37°C for four hours. Activity is measured by reading sample fluorescence at λ=510 nm following excitation of the reaction product at λ=400 nm.

SIRT2 Inhibitor Screening Assay Kit (Fluorometric)
K322-100 each
EUR 718.8

p300 Inhibitor Screening Assay Kit (Fluorometric)
K346-100 each
EUR 777.6

TACE Inhibitor Screening Assay Kit ( Fluorometric)
K366-100 each
EUR 705.6

BTLA:HVEM[Biotinylated] Inhibitor Screening Assay Kit
72008 96 rxns.
EUR 1070
Description: The BTLA:HVEM[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of BTLA:HVEM signaling. The key to this kit is the high sensitivity of detection of biotin-labeled HVEM by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, BTLA is coated on a 96-well plate. Next, HVEM is incubated with BTLA on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

KEAP1-Nrf2 Inhibitor Screening Assay Kit
72020 96 rxns.
EUR 960
Description: The Keap1:Nrf2 Inhibitor Screening Assay Kit is designed for_x000D_identification of inhibitors of Keap1:Nrf2 binding using fluorescence polarization. Using this kit, only one simple step on a microtiter plate is required for_x000D_Keap1:Nrf2 inhibitor screening reactions. The Keap1 protein and fluorescently labeled_x000D_Nrf2 peptide are incubated with a sample containing testing inhibitors for 30 minutes._x000D_The change in fluorescent polarization can then be measured using a fluorescence_x000D_reader.

Mouse IDO1 Inhibitor Screening Assay Kit
72041 96 rxns.
EUR 745
Description: The Mouse IDO1 Inhibitor Screening Assay Kit is designed to measure inhibition of the murine IDO1 enzyme. This kit is simple to use. Inhibitor and enzyme are added to a sample containing L-Trp substrate. After a room temperature incubation, activity is determined by measuring the absorption of reaction product at l=320-325 nm.

Mouse IDO2 Inhibitor Screening Assay Kit
72042 96 rxns.
EUR 860
Description: The IDO2 Inhibitor Screening Assay Kit is designed to measure mouse IDO2_x000D_enzyme inhibition. The Mouse IDO2 Inhibitor Screening Assay Kit is_x000D_simple to use. Inhibitor and enzyme are added to a sample containing L-Trp substrate. After a_x000D_room temperature incubation, activity is determined by measuring the absorption of reaction_x000D_product at l=320 - 325 nm._x000D_BACKGROUND: L-tryptophan

GITRL:GITR[Biotinylated] Inhibitor Screening Assay Kit
72061 96 rxns.
EUR 1070
Description: The GITR:GITRL[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of GITR:GITRL signaling. The key to this kit is the high sensitivity of detection of biotin-labeled GITR by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, GITRL is coated on a 96-well plate. Next, GITR is incubated with GITRL on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader._x000D__x000D_

Cathepsin S Inhibitor Screening Assay Kit
79588 96 rxns.
EUR 515
Description: The Cathepsin S Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin S for screening and profiling applications. The Cathepsin S assay kit comes in a convenient 96-well format, with purified Cathepsin S, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions. In addition, the kit includes the cathepsin inhibitor E64 for use as a control inhibitor.

Cathepsin V Inhibitor Screening Assay Kit
79589 96 rxns.
EUR 515
Description: The Cathepsin V Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin V for screening and profiling applications. The Cathepsin V assay kit comes in a convenient 96-well format, with purified Cathepsin V, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions. In addition, the kit includes the cathepsin inhibitor E64 for use as a control inhibitor.

Cathepsin B Inhibitor Screening Assay Kit
79590 96 rxns.
EUR 515
Description: The Cathepsin B Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin B for screening and profiling applications. The Cathepsin B assay kit comes in a convenient 96-well format, with purified Cathepsin B, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions. In addition, the kit includes the cathepsin inhibitor E64 for use as a control inhibitor.

Cathepsin L Inhibitor Screening Assay Kit
79591 96 rxns.
EUR 540
Description: The Cathepsin L Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin L for screening and profiling applications. The Cathepsin L assay kit comes in a convenient 96-well format, with purified Cathepsin L, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions. In addition, the kit includes the cathepsin inhibitor E64 for use as a control inhibitor.

BAFF:BCMA[Biotinylated] Inhibitor Screening Assay Kit
79667 96 rxns.
EUR 765
Description: The BAFF:BCMA[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of BAFF:BCMA signaling.The key to this kit is the high sensitivity of detection of biotin-labeled BCMA by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, BAFF is coated on a 96-well plate. Next, BCMA is incubated with BAFF on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

ICOSL:ICOS[Biotinylated] Inhibitor Screening Assay Kit
79673 96 rxns.
EUR 725
Description: The ICOSL:ICOS[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of ICOS:ICOSL signaling. The key to this kit is the high sensitivity of detection of biotin-labeled ICOS by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, ICOSL is coated on a 96-well plate. Next, ICOS is incubated with ICOSL on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

LIGHT:HVEM [Biotinylated] Inhibitor Screening Assay Kit
79684 96 rxns.
EUR 1040
Description: The LIGHT:HVEM[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of LIGHT:HVEM signaling. The key to this kit is the high sensitivity of detection of biotin-labeled HVEM by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, LIGHT is coated on a 96-well plate. Next, HVEM is incubated with LIGHT on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

BCMA:APRIL[Biotinylated] Inhibitor Screening Assay Kit
79722 96 rxns.
EUR 765
Description: The BCMA:APRIL[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of BCMA:APRIL. The key to this kit is the high sensitivity of detection of biotin-labeled APRIL by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, BCMA is coated on a 96-well plate. Next, biotinylated APRIL is incubated with BCMA on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

CD112R:CD112[Biotinylated] Inhibitor Screening Assay Kit
79732 96 rxns.
EUR 830
Description: The CD112R:CD112[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD112R-CD112. The key to this kit is the high sensitivity of detection of biotin-labeled CD112 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CD112R is coated on a 96-well plate. Next, CD112 is incubated with CD112R on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader._x000D_

LTβR:LIGHT[Biotinylated] Inhibitor Screening Assay Kit
79808 96 rxns.
EUR 1040
Description: The LTβR:LIGHT[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of LIGHT binding to LTβR . This kit comes in a convenient 96-well format, with biotin-labeled LIGHT, purified LTβR , streptavidin-labeled HRP, and assay buffer for 100 binding reactions. The key to this kit is the high sensitivity of detection of biotin-labeled LIGHT by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, LTβR is coated on a 96-well plate. Next, biotinylated LIGHT is incubated with LTβR on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

Cathepsin F Inhibitor Screening Assay Kit
79971 96 rxns.
EUR 515
Description: The Cathepsin F Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin F for screening and profiling applications. 

BRD3 (BD1) Inhibitor Screening Assay Kit
32513 384 rxns.
EUR 510
Description: The BRD3 (BD1) Inhibitor Screening Assay Kit is designed to measure the inhibition of BRD3 bromodomain 1 (BD1) from binding to its substrate. The key to the BRD3 (BD1) Inhibitor Screening Assay Kit is the highly specific binding of the BRD3 bromodomain 1 to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRD3 bromodomain 1 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

BRD4 (BD1) Inhibitor Screening Assay Kit
32514 384 rxns.
EUR 510
Description: The BRD4 (BD1) Inhibitor Screening Assay Kit is designed to measure the inhibition of BRD4 bromodomain 1 (BD1) from binding to its substrate. The key to the BRD4 (BD1) Inhibitor Screening Assay Kit is the highly specific binding of the BRD4 bromodomain 1 to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRD4 bromodomain 1 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

BRD9 (BD1) Inhibitor Screening Assay Kit
32519 384 rxns.
EUR 510
Description: The BRD9 Inhibitor Screening Assay Kit is designed to measure the inhibition of BRD9 binding to its substrate. The key to the BRD9 Inhibitor Screening Assay Kit is the specific binding of the BRD9 bromodomain to an acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRD9 and an inhibitor of choice is incubated with the biotinylated substrate. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

BRD2 (BD2) Inhibitor Screening Assay Kit
32522 384 rxns.
EUR 510
Description: The BRD2 (BD2) Inhibitor Screening Assay Kit is designed to measure the inhibition of BRD2 bromodomain 2 (BD2) from binding to its substrate. The key to the BRD2 (BD2) Inhibitor Screening Assay Kit is the highly specific binding of the BRD2 bromodomain 2 to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRD2 bromodomain 2 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

BRD3 (BD2) Inhibitor Screening Assay Kit
32523 384 rxns.
EUR 510
Description: The BRD3 (BD2) Inhibitor Screening Assay Kit is designed to measure the inhibition of BRD3 bromodomain 2 (BD2) from binding to its substrate. The key to the BRD3 (BD2) Inhibitor Screening Assay Kit is the highly specific binding of the BRD3 bromodomain 2 to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRD3 bromodomain 2 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

BRD4 (BD2) Inhibitor Screening Assay Kit
32524 384 rxns.
EUR 510
Description: The BRD4 (BD2) Inhibitor Screening Assay Kit is designed to measure the inhibition of BRD4 bromodomain 2 (BD2) binding to its substrate. The key to the BRD4 (BD2) Inhibitor Screening Assay Kit is the highly specific binding of the BRD4 bromodomain 2 to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRD4 bromodomain 2 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

TAF1L (BD2) Inhibitor Screening Assay Kit
32602 384 rxns.
EUR 1025
Description: The TAF1L (BD2) Inhibitor Screening Assay Kit is designed to measure the inhibition of TAF1L binding to its substrate. The key to the assay kit is specific binding of the TAF1L bromodomain 2 (a.a. 1517-1649) to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing TAF1L and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

SMARCA4/BRG1 Inhibitor Screening Assay Kit
32609 384 rxns.
EUR 510
Description: The BRG1 Inhibitor Screening Assay Kit is designed to measure the inhibition of BRG1 binding to its substrate. The key to the BRG1 Inhibitor Screening Assay Kit is the specific binding of the BRG1 bromodomain to an acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing BRG1 and an inhibitor of choice is incubated with the biotinylated substrate. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

TAF1 (BD2) Inhibitor Screening Assay Kit
32624 384 rxns.
EUR 1025
Description: The TAF1 (BD2) Inhibitor Screening Assay Kit is designed to measure the inhibition of TAF1 (BD2) binding to its substrate. The key to the TAF1 (BD2) Inhibitor Screening Assay Kit is the specific binding of the TAF1 bromodomain 2 (a.a. 1519-1651) to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing TAF1 (BD2) and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (384)
72047 384 rxns.
EUR 1070
Description: The IDO1 Fluorogenic Inhibitor Screening Assay Kit is designed to measure enzyme inhibition of indoleamine 2,3-dioxygenase 1 (IDO1). The IDO1 Fluorogenic Inhibitor Screening Assay Kit is simple to use and detects fluorescence at long wavelengths, which minimizes potential errors due to compound interference. In the assay, the inhibitor and enzyme are added to a sample containing L-Trp substrate. After a 1 hour incubation at room temperature, the fluorescence solution is added and incubated at 37°C for four hours. Activity is measured by reading sample fluorescence at λ=510 nm following excitation of the reaction product at λ=400 nm.

Human TDO Fluorogenic Inhibitor Screening Assay Kit (384)
72049 384 rxns.
EUR 1125
Description: The TDO Fluorogenic Inhibitor Screening Assay Kit is designed to measure enzyme inhibition of tryptophan 2,3-dioxygenase (TDO). The TDO Fluorogenic Inhibitor Screening Assay Kit is simple to use and detects fluorescence at long wavelengths, which minimizes potential errors due to compound interference. In the assay, the inhibitor and enzyme are added to a sample containing L-Trp substrate. After a 1 hour incubation at room temperature, the fluorescence solution is added and incubated at 37°C for four hours. Activity is measured by reading sample fluorescence at λ=510 nm following excitation of the reaction product at λ=400 nm.

QuantiChrom™ Hyaluronidase Inhibitor Screening Assay Kit
DIHY-100 100
EUR 489
Description: For evaluation and high-throughput screen (HTS) of hyaluronidase modulators. Key Features: Rapid and reliable. Entire assay can be completed in 30 min. Simple and Convenient. Simple procedure with an enzymatic reaction and addition of stop reagent. No wash or reagent transfer steps involved. Robust and amenable to HTS. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: Turbidimetric (OD 600nm). Samples: Test Compounds, Hyaluronidase Inhibitors. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests.

QuantiFluo™ Urokinase Inhibitor Screening Assay Kit
DUKI-100 100
EUR 389
Description: For evaluation of drugs and screening potential inhibitors of urokinase. Key Features: Safe. Non-radioactive assay. Fast. Assay is completed within a 30 minute reaction time. Homogeneous "mix-incubate-measure" type assay. Can be readily automated to assay thousands of samples per day. Method: FL 380/450 nm; Samples: Purified protein and protein extracts; Species: All. Procedure: assay takes 30min; Size: 100 tests. Detection Limit: 0.04 U/L.

HSP90α (C-Terminal) Inhibitor Screening Assay Kit
50317 384 rxns.
EUR 1015
Description: The HSP90α (C-Terminal) Inhibitor Screening Assay Kit is designed to measure the inhibition of HSP90α binding to its protein target PPID (also known as Cyclophilin D). With this kit, only three simple steps on a microtiter plate are required. First, a sample containing HSP90α, PPID, and an inhibitor of choice is incubated for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

CD38 Inhibitor Screening Assay Kit (Cyclase Activity)
71275 96 rxns.
EUR 890
Description: The CD38 Inhibitor Screening Assay Kit (Cyclase Activity) is designed to measure the cyclase activity of CD38 for screening and profiling applications. The CD38 assay kit comes in a convenient 96-well format, with purified recombinant CD38 enzyme, its substrate nicotinamide guanine dinucleotide (NGD+), and CD38 assay buffer for 100 enzyme reactions. In addition, the kit includes the CD38 inhibitor quercitin for use as an inhibitor control.

CD137[Biotinylated]:CD137L Inhibitor Screening Assay Kit
72025 96 rxns.
EUR 1130
Description: The CD137:CD137L Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD137:CD137L interaction. The key to this kit is the high sensitivity of detection of biotin-labeled CD137 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CD137L is coated on a 96-well plate. Next, CD137-biotin is incubated with CD137L on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

OX40[Biotinylated]:OX40L Inhibitor Screening Assay Kit
72045 96 rxns.
EUR 1070
Description: The OX40[Biotinylated]:OX40L Inhibitor Screening Assay Kit is designed for_x000D_screening and profiling inhibitors of OX40:OX40L interaction. The key to this kit is the high sensitivity of detection of biotinlabeled_x000D_OX40 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for_x000D_the assay. First, OX40L is coated on a 96-well plate. Next, OX40-biotin is incubated with OX40L_x000D_on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP_x000D_substrate to produce chemiluminescence, which can then be measured using a_x000D_chemiluminescence reader.

CD40:CD40L[Biotinylated] Inhibitor Screening Assay Kit
79257 96 rxns.
EUR 745
Description: The CD40:CD40L[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD40:CD40L signaling. This kit comes in a convenient 96-well format, with biotin-labeled CD40, purified CD40L, streptavidin-labeled HRP, and assay buffer for 100 binding reactions. The key to this kit is the high sensitivity of detection of biotin-labeled CD40 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CD40L is coated on a 96-well plate. Next, CD40 is incubated with CD40L on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

CD38 Inhibitor Screening Assay Kit (Hydrolase Activity)
79287 96 rxns.
EUR 890
Description: The CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of CD38 for screening and profiling applications. The CD38 assay kit comes in a convenient 96-well format, with purified recombinant CD38 enzyme, its substrate N6-etheno-NAD (ε-NAD), and CD38 assay buffer for 100 enzyme reactions. In addition, the kit includes the CD38 inhibitor apigenin for use as a control inhibitor.

CD38 Inhibitor Screening Assay Kit (Hydrolase Activity)
79672 384 rxns.
EUR 1120
Description: The CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of CD38 for screening and profiling applications.

CD27:CD70[Biotinylated] Inhibitor Screening Assay Kit
79695 96 rxns.
EUR 1070
Description: The CD27:CD70[Biotinylated] Inhibitor Screening Assay Kit is designed for_x000D_ screening and profiling inhibitors of CD27:CD70 signaling. This kit comes in a convenient 96- well_x000D_ format, with biotin-labeled CD70, purified CD27, streptavidin-labeled HRP, and assay buffer for_x000D_100 binding reactions. The key to this kit is the high sensitivity of detection of biotin-labeled CD70_x000D_by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay._x000D_ First, CD27 is coated on a 96-well plate. Next, CD70 is incubated with CD27 on the plate. Finally,_x000D_ the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce_x000D_ chemiluminescence, which can be measured using a chemiluminescence reader.

LAG3:FGL1[Biotinylated] Inhibitor Screening Assay Kit
79789 96 rxns.
EUR 830
Description: The LAG3:FGL1[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of LAG3:FGL1. The key to this kit is the high sensitivity of detection of biotin-labeled FGL1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, LAG3 is attached on a nickel-coated 96-well plate. Next, biotinylated FGL1 is incubated with LAG3 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

TAF1L (BD1/BD2) Inhibitor Screening Assay Kit
32603 384 rxns.
EUR 1025
Description: The TAF1L (BD1 + BD2) Inhibitor Screening Assay Kit is designed to measure the inhibition of TAF1L binding to its substrate. The key to the assay kit is specific binding of the TAF1L bromodomains 1 and 2 (a.a. 1398-1649) to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing TAF1L and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

TAF1 (BD1/BD2) Inhibitor Screening Assay Kit
32604 384 rxns.
EUR 1025
Description: The TAF1 (BD 1 + BD2) Inhibitor Screening Assay Kit is designed to measure the inhibition of TAF1 binding to its substrate. The key to the kit is the specific binding of the tandem TAF1 bromodomains to the acetylated histone substrate. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing TAF1 and an inhibitor of choice is incubated with the biotinylated substrate for thirty minutes. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts

Human IMPDH Inhibitor Screening Assay