Cell Meter Fluorimetric Intracellular
To Order Contact us: bjorn@lembcke.dk
Cell Meter™ Fluorimetric Intracellular Total ROS Activity Assay Kit*Orange Fluorescence* |
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22902 | AAT Bioquest | 200 Tests | EUR 262.8 |
Cell Meter™ Fluorimetric Intracellular Peroxynitrite Assay Kit *Optimized for Flow Cytometry* |
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16317 | AAT Bioquest | 100 Tests | EUR 420 |
Cell Meter™ Fluorimetric Intracellular Total ROS Activity Assay Kit*Deep Red Fluorescence* |
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22903 | AAT Bioquest | 200 Tests | EUR 262.8 |
Cell Meter™ Fluorimetric Cell Cytotoxicity Assay Kit |
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22781 | AAT Bioquest | 1000 Tests | EUR 262.8 |
Cell Meter™ Fluorimetric Cell Cytotoxicity Assay Kit |
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22782 | AAT Bioquest | 5000 Tests | EUR 897 |
Cell Meter™ Fluorimetric Intracellular Total ROS Activity Assay Kit*Optimized for Flow Cytometry* |
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22904 | AAT Bioquest | 100 Tests | EUR 367.2 |
Cell Meter™ Fluorimetric Cellular Voltage Assay Kit |
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35000 | AAT Bioquest | 100 Tests | EUR 746 |
Cell Meter™ Intracellular Fluorimetric Hydrogen Peroxide Assay Kit *Blue Fluorescence Optimized for Flow Cytometry* |
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11505 | AAT Bioquest | 100 Tests | EUR 315.6 |
Cell Meter™ Intracellular Fluorimetric Hydrogen Peroxide Assay Kit *Green Fluorescence Optimized for Flow Cytometry* |
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11506 | AAT Bioquest | 100 Tests | EUR 315.6 |
Cell Meter™ Fluorimetric Phagocytosis Assay Kit *Red Fluorescence* |
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21225 | AAT Bioquest | 100 Tests | EUR 367.2 |
Cell Meter™ Fluorimetric Cellular Lipid Peroxidation Assay Kit |
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22906 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ Fluorimetric Intracellular Nitric Oxide (NO) Activity Assay Kit *Orange Fluorescence Optimized for Microplate Reader* |
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16350 | AAT Bioquest | 200 Tests | EUR 420 |
Cell Meter™ Fluorimetric Intracellular Nitric Oxide (NO) Activity Assay Kit *Orange Fluorescence Optimized for Flow Cytometry* |
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16351 | AAT Bioquest | 100 Tests | EUR 420 |
Cell Meter™ Fluorimetric Intracellular Nitric Oxide (NO) Activity Assay Kit *Red Fluorescence Optimized for Flow Cytometry* |
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16356 | AAT Bioquest | 100 Tests | EUR 420 |
Cell Meter™ Fluorimetric Intracellular Nitric Oxide (NO) Activity Assay Kit *NIR Fluorescence Optimized for Microplate Reader* |
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16359 | AAT Bioquest | 200 Tests | EUR 420 |
Cell Meter™ Fluorimetric Intracellular Nitric Oxide (NO) Activity Assay Kit *NIR Fluorescence Optimized for Flow Cytometry* |
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16360 | AAT Bioquest | 100 Tests | EUR 420 |
Cell Meter™ Intracellular NADH/NADPH Fluorescence Imaging Kit |
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15290 | AAT Bioquest | 100 Tests | EUR 576 |
Cell Meter™ Fluorimetric Mitochondrial Superoxide Activity Assay Kit *Green Fluorescence* |
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16060 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ Intracellular NADH/NADPH Flow Cytometric Analysis Kit |
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15291 | AAT Bioquest | 100 Tests | EUR 576 |
Cell Meter™ Intracellular Colorimetric Lipid Peroxidation (MDA) Assay Kit |
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15991 | AAT Bioquest | 200 tests | EUR 471.6 |
Cell Meter™ Intracellular GSH Assay Kit *Optimized for Flow Cytometry* |
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22810 | AAT Bioquest | 100 Tests | EUR 262.8 |
Cell Meter™ Fluorimetric Mitochondrial Superoxide Activity Assay Kit*Optimized for Flow Cytometry* |
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22970 | AAT Bioquest | 100 Tests | EUR 367.2 |
Cell Meter™ Fluorimetric Mitochondrial Superoxide Activity Assay Kit*Optimized for Microplate Reader* |
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22971 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ Intracellular NADH/NADPH Fluorescence Imaging Kit *Deep Red Fluorescence* |
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15295 | AAT Bioquest | 100 Tests | EUR 558 |
Cell Meter™ Fluorimetric Live Cell Cycle Assay Kit *Green Fluorescence Optimized for Flow Cytometry* |
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22841 | AAT Bioquest | 100 Tests | EUR 262.8 |
Cell Meter™ Fluorimetric Fixed Cell Cycle Assay Kit *Red Fluorescence Optimized for Flow Cytometry* |
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22842 | AAT Bioquest | 100 Tests | EUR 262.8 |
Cell Meter™ Fluorimetric Live Cell Cycle Assay Kit *Red Fluorescence Optimized for Flow Cytometry* |
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22860 | AAT Bioquest | 100 tests | EUR 367.2 |
OxiSelect Intracellular ROS Assay Kit (Green Fluorescence) |
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STA-342 | Cell Biolabs | 96 assays | EUR 762 |
Description: The OxiSelect ROS Assay Kit is a cell-based assay for measuring hydroxyl, peroxyl, and other reactive oxygen species activity within a cell. The assay employs the cell-permeable fluorogenic probe DCFH-DA, which diffuses into cells and is deacetylcated by cellular esterases into the non-fluorescent DCFH (Figure 1). In the presence of ROS, DCFH is rapidly oxidized to highly fluorescent DCF. Fluorescence is read on a standard fluorometric plate reader. |
OxiSelect Intracellular ROS Assay Kit (Green Fluorescence) |
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STA-342-5 | Cell Biolabs | 5 x 96 assays | EUR 3058.8 |
Description: The OxiSelect ROS Assay Kit is a cell-based assay for measuring hydroxyl, peroxyl, and other reactive oxygen species activity within a cell. The assay employs the cell-permeable fluorogenic probe DCFH-DA, which diffuses into cells and is deacetylcated by cellular esterases into the non-fluorescent DCFH (Figure 1). In the presence of ROS, DCFH is rapidly oxidized to highly fluorescent DCF. Fluorescence is read on a standard fluorometric plate reader. |
Cell Meter™ Fluorimetric Live Cell Cycle Assay Kit *Optimized for 405 nm Violet Laser Excitation* |
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22845 | AAT Bioquest | 100 Tests | EUR 262.8 |
Cell Meter™ Intracellular NADH/NADPH Flow Cytometric Analysis Kit *Deep Red Fluorescence* |
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15296 | AAT Bioquest | 100 Tests | EUR 558 |
OxiSelect Intracellular Nitric Oxide (NO) Assay Kit (Fluorometric) |
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STA-800 | Cell Biolabs | 96 assays | EUR 588 |
Description: The OxiSelect Intracellular Nitric Oxide Assay Kit is a cell-based assay for rapid detection of intracellular NO or NOS activity in cultured cells. In brief, the cell-permeant NO probe passively diffuses into cells and is deacetylated by cellular esterases to a non-fluorescent intermediate. When intracellular nitric oxide encounters this intermediate, it rapidly oxidizes to a highly fluorescent, triazolo-fluorescein analog. The fluorescence intensity is proportional to the NO levels within the cell cytosol (detection limit of ~3 nM). The kit?s provided Nitric Oxide Fluorometric Probe is NO specific, has excellent photostablity and pH stability, and is detected with standard fluorescein filters. The probe is suitable for flow cytometry, fluorescent microscopy, and fluorescent microplate detection. Each kit provides sufficient reagents to perform up to 96 assays, including blanks, standards, and unknown samples. |
OxiSelect Intracellular Nitric Oxide (NO) Assay Kit (Fluorometric) |
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STA-800-5 | Cell Biolabs | 5 x 96 assays | EUR 2307.6 |
Description: The OxiSelect Intracellular Nitric Oxide Assay Kit is a cell-based assay for rapid detection of intracellular NO or NOS activity in cultured cells. In brief, the cell-permeant NO probe passively diffuses into cells and is deacetylated by cellular esterases to a non-fluorescent intermediate. When intracellular nitric oxide encounters this intermediate, it rapidly oxidizes to a highly fluorescent, triazolo-fluorescein analog. The fluorescence intensity is proportional to the NO levels within the cell cytosol (detection limit of ~3 nM). The kit?s provided Nitric Oxide Fluorometric Probe is NO specific, has excellent photostablity and pH stability, and is detected with standard fluorescein filters. The probe is suitable for flow cytometry, fluorescent microscopy, and fluorescent microplate detection. Each kit provides sufficient reagents to perform up to 96 assays, including blanks, standards, and unknown samples. |
Cell Meter™ Generic Fluorimetric Caspase Activity Assay Kit *Green Fluorescence Optimized for Flow Cytometry* |
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22821 | AAT Bioquest | 100 Tests | EUR 262.8 |
Cell Meter™ Generic Fluorimetric Caspase Binding Assay Kit *Red Fluorescence Optimized for Flow Cytometry* |
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22822 | AAT Bioquest | 100 Tests | EUR 262.8 |
OxiSelect Intracellular ROS Assay Kit (Green Fluorescence), Trial Size |
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STA-342-T | Cell Biolabs | 20 assays | EUR 414 |
Description: The OxiSelect ROS Assay Kit is a cell-based assay for measuring hydroxyl, peroxyl, and other reactive oxygen species activity within a cell. The assay employs the cell-permeable fluorogenic probe DCFH-DA, which diffuses into cells and is deacetylcated by cellular esterases into the non-fluorescent DCFH (Figure 1). In the presence of ROS, DCFH is rapidly oxidized to highly fluorescent DCF. Fluorescence is read on a standard fluorometric plate reader. |
Cell Meter™ Intracellular GSH Assay Kit *Optimized for Flow Cytometry with 405 nm excitation* |
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22809 | AAT Bioquest | 100 Tests | EUR 222 |
WPA CO8000 Cell Density Meter |
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COL3430 | Scientific Laboratory Supplies | EACH | EUR 714.78 |
Meter Kit |
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STARA2114 | Scientific Laboratory Supplies | EACH | EUR 1255.14 |
Cell Meter™ Cell Adhesion Assay Kit |
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23010 | AAT Bioquest | 100 Tests | EUR 372 |
meter bio-electronic |
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C3050 | Consort | ea | EUR 1436.4 |
S210 pH meter |
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PHM0052 | Scientific Laboratory Supplies | EACH | EUR 741 |
Soil pH meter |
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PHM0326 | Scientific Laboratory Supplies | EACH | EUR 563.16 |
Food pH meter |
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PHM0332 | Scientific Laboratory Supplies | EACH | EUR 623.58 |
Meat pH meter |
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PHM0334 | Scientific Laboratory Supplies | EACH | EUR 623.58 |
Portable Chlorine meter |
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WAT1074 | Scientific Laboratory Supplies | EACH | EUR 489.06 |
Chlorine meter standards |
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WAT1076 | Scientific Laboratory Supplies | EACH | EUR 269.04 |
Hanna Turbidity Meter |
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WAT1550 | Scientific Laboratory Supplies | EACH | EUR 1162.8 |
Bench turbidity meter |
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WAT7300 | Scientific Laboratory Supplies | EACH | EUR 2065.68 |
Portable Turbidity meter |
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WAT7302 | Scientific Laboratory Supplies | EACH | EUR 1226.64 |
Cell Meter™ Colorimetric Cell Cytotoxicity Assay Kit |
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22780 | AAT Bioquest | 1000 Tests | EUR 262.8 |
Cell Meter™ Colorimetric MTT Cell Proliferation Kit |
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22768 | AAT Bioquest | 1000 Tests | EUR 318 |
Cell Meter™ Colorimetric MTT Cell Proliferation Kit |
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22769 | AAT Bioquest | 5000 Tests | EUR 805 |
Cell Meter™ Colorimetric Cell Cytotoxicity Assay Kit |
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22779 | AAT Bioquest | 5000 Tests | EUR 897 |
Cell Meter™ Live Cell ATP Assay Kit |
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23015 | AAT Bioquest | 100 Tests | EUR 360 |
Cell Meter™ Autophagy Fluorescence Imaging Kit |
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23001 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ Bacterial Viability Assay Kit |
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22400 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ BX520 fixable viability dye |
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22510 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ BX590 fixable viability dye |
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22514 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ BX650 fixable viability dye |
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22520 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ IX830 fixable viability dye |
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22529 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ RX660 fixable viability dye |
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22530 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ RX700 fixable viability dye |
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22532 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ RX780 fixable viability dye |
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22536 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ VX450 fixable viability dye |
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22540 | AAT Bioquest | 200 Tests | EUR 211 |
Cell Meter™ VX500 fixable viability dye |
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22542 | AAT Bioquest | 200 Tests | EUR 211 |
Adrb3 (Intracellular) Antibody |
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abx431082-200ul | Abbexa | 200 ul | EUR 343.2 |
Cell Meter™ Colorimetric WST-8 Cell Quantification Kit |
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22770 | AAT Bioquest | 1000 Tests | EUR 262.8 |
Cell Meter™ Colorimetric WST-8 Cell Quantification Kit |
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22771 | AAT Bioquest | 5000 Tests | EUR 576 |
Cell Meter™ Cell Viability Assay Kit *Red Fluorescence* |
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22783 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ Cell Viability Assay Kit *Blue Fluorescence* |
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22785 | AAT Bioquest | 500 Tests | EUR 262.8 |
Cell Meter™ Cell Viability Assay Kit *Green Fluorescence* |
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22786 | AAT Bioquest | 500 Tests | EUR 262.8 |
pH Meter Calibration Kit |
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55-0001 | Medicago | 1 Kit | EUR 121.2 |
AI9100 Melting Point Meter |
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MEL1000 | Scientific Laboratory Supplies | EACH | EUR 1374.84 |
AI9200 Melting Point Meter |
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MEL1010 | Scientific Laboratory Supplies | EACH | EUR 1634.76 |
FiveEasy F20 F20-Meter |
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PHM0045 | Scientific Laboratory Supplies | EACH | EUR 442.32 |
Edge Dissolved Oxygen meter |
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PHM0340 | Scientific Laboratory Supplies | EACH | EUR 672.6 |
550 handheld PH meter |
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PHM1102 | Scientific Laboratory Supplies | EACH | EUR 175.56 |
570 handheld PH meter |
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PHM1106 | Scientific Laboratory Supplies | EACH | EUR 235.98 |
Multi-parameter meter wproof |
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PHM3082 | Scientific Laboratory Supplies | EACH | EUR 1787.52 |
Hanna edge pH Meter |
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PHM4092 | Scientific Laboratory Supplies | EACH | EUR 491.34 |
FiveEasy F30 F30-Meter |
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CON0042 | Scientific Laboratory Supplies | EACH | EUR 769.5 |
Jenway Conductivity Meter 4510 |
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CON1220 | Scientific Laboratory Supplies | EACH | EUR 767.22 |
Jenway Conductivity Meter 4520 |
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CON1230 | Scientific Laboratory Supplies | EACH | EUR 1035.12 |
Hanna 8733 Conductivity Meter |
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CON3230 | Scientific Laboratory Supplies | EACH | EUR 633.84 |
Hanna 9033 Conductivity Meter |
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CON3240 | Scientific Laboratory Supplies | EACH | EUR 726.18 |
Densito Portable Density Meter |
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DEN1014 | Scientific Laboratory Supplies | EACH | EUR 2815.8 |
DensitoPro Portable Density Meter |
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DEN1016 | Scientific Laboratory Supplies | EACH | EUR 3152.1 |
Portable Dissolved Oxygen meter |
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DIS1028 | Scientific Laboratory Supplies | EACH | EUR 718.2 |
Jenway DO2 Meter 9500 |
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DIS2110 | Scientific Laboratory Supplies | EACH | EUR 1388.52 |
Sherwood 926S Chloride Meter |
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CHL2000 | Scientific Laboratory Supplies | EACH | EUR 5670.36 |
Hanna FreeandTotal Chlorine Meter |
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WAT1504 | Scientific Laboratory Supplies | EACH | EUR 380.76 |
Hach TL2300 Turbidimeter Meter |
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WAT3670 | Scientific Laboratory Supplies | EACH | EUR 6862.8 |
Intracellular Hydrogen Peroxide Detection Kit (cell-based) |
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K204-200 | Biovision | each | EUR 379.2 |
EZCell? Intracellular Zinc Staining Kit (Cell-Based) |
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K525-50 | Biovision | each | EUR 679.2 |
Cell Meter™ Autophagy Assay Kit *Blue Fluorescence* |
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23000 | AAT Bioquest | 200 Tests | EUR 262.8 |
Cell Meter™ Autophagy Assay Kit *Green Fluorescence* |
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23002 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ Flow Cytometric Calcium Assay Kit |
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36310 | AAT Bioquest | 100 Tests | EUR 576 |
Cell Meter™ Colorimetric Antioxidant Activity Assay Kit |
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15900 | AAT Bioquest | 200 Tests | EUR 367.2 |
Cell Meter™ Fluorescence Gap Junction Tracing Kit |
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23600 | AAT Bioquest | 100 Tests | EUR 425 |
PhosphoWorks™ Fluorimetric ATP Assay Kit |
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21620 | AAT Bioquest | 100 Tests | EUR 471.6 |
Portelite™ Fluorimetric Protein Quantitation Kit |
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11110 | AAT Bioquest | 200 Tests | EUR 158.4 |
Amplite™ Fluorimetric Pyruvate Assay Kit |
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13820 | AAT Bioquest | 200 Tests | EUR 367.2 |
Amplite™ Fluorimetric Glycerol Assay Kit |
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13833 | AAT Bioquest | 200 Tests | EUR 420 |
Amplite™ Fluorimetric Xanthine Assay Kit |
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13843 | AAT Bioquest | 200 Tests | EUR 420 |
Amplite™ Fluorimetric Aldehyde Quantitation Kit |
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10052 | AAT Bioquest | 200 Tests | EUR 262.8 |
Amplite® Fluorimetric Melanin Assay Kit |
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11310 | AAT Bioquest | 100 Tests | EUR 334 |
Amplite® Fluorimetric Tyrosinase Assay Kit |
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11312 | AAT Bioquest | 100 Tests | EUR 446 |
Amplite® Fluorimetric Endotoxin Detection Kit |
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60006 | AAT Bioquest | 100 Tests | EUR 316 |
Visfatin Intracellular ELISA Kit |
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55R-1416 | Fitzgerald | 100 assays | EUR 1794 |
Description: ELISA kit for detection of Intracellular Visfatin in the research laboratory |
Cell Navigator™ Fluorimetric Lipid Droplet Assay Kit *Green Fluorescence* |
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22730 | AAT Bioquest | 200 Tests | EUR 262.8 |
Cell Navigator™ Fluorimetric Lipid Droplet Assay Kit *Red Fluorescence* |
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22735 | AAT Bioquest | 500 Tests | EUR 262.8 |
TIA-1 Antibody / T-Cell Intracellular Antigen-1 |
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V8438-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: TIA-1 (T-cell intracytoplasmic antigen) is a cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kDa protein thought to be derived from the carboxyl terminus of the 40kDa product by proteolytic processing. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. |
TIA-1 Antibody / T-Cell Intracellular Antigen-1 |
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V8438-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: TIA-1 (T-cell intracytoplasmic antigen) is a cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kDa protein thought to be derived from the carboxyl terminus of the 40kDa product by proteolytic processing. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. |
TIA-1 Antibody / T-Cell Intracellular Antigen-1 |
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V8438SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: TIA-1 (T-cell intracytoplasmic antigen) is a cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kDa protein thought to be derived from the carboxyl terminus of the 40kDa product by proteolytic processing. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. |
TIA-1 Antibody / T-Cell Intracellular Antigen-1 |
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V7235-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: T-Cell Intracellular Antigen-1 is a cytoplasmic granule-associated protein expressed in lymphocytes processing cytolytic potential. It is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kDa protein thought to be derived from the carboxyl terminus of the 40kDa product by proteolytic processing. TIA-1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. |
TIA-1 Antibody / T-Cell Intracellular Antigen-1 |
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V7235-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: T-Cell Intracellular Antigen-1 is a cytoplasmic granule-associated protein expressed in lymphocytes processing cytolytic potential. It is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kDa protein thought to be derived from the carboxyl terminus of the 40kDa product by proteolytic processing. TIA-1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. |
TIA-1 Antibody / T-Cell Intracellular Antigen-1 |
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V7235SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: T-Cell Intracellular Antigen-1 is a cytoplasmic granule-associated protein expressed in lymphocytes processing cytolytic potential. It is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kDa protein thought to be derived from the carboxyl terminus of the 40kDa product by proteolytic processing. TIA-1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. |